Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth
Authors
Biscans, AnnabelleUMass Chan Affiliations
RNA Therapeutics InstituteDocument Type
Journal ArticlePublication Date
2018-11-06Keywords
nucleotide and nucleoside synthesisorigin of life
prebiotic chemistry
Biochemistry
Biology
Chemistry
Nucleic Acids, Nucleotides, and Nucleosides
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Understanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple feedstocks under prebiotically plausible conditions. It is well established that evolution of life involved RNA which plays central roles in both inheritance and catalysis. In this review, we present historically important and recently published articles aimed at understanding the emergence of RNA nucleosides and nucleotides on the early Earth.Source
Life (Basel). 2018 Nov 6;8(4). pii: life8040057. doi: 10.3390/life8040057. Link to article on publisher's site
DOI
10.3390/life8040057Permanent Link to this Item
http://hdl.handle.net/20.500.14038/40869PubMed ID
30404133Related Resources
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© 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).Distribution License
http://creativecommons.org/licenses/by/4.0/ae974a485f413a2113503eed53cd6c53
10.3390/life8040057
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Except where otherwise noted, this item's license is described as © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).