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dc.contributor.authorBiscans, Annabelle
dc.date2022-08-11T08:09:51.000
dc.date.accessioned2022-08-23T16:46:23Z
dc.date.available2022-08-23T16:46:23Z
dc.date.issued2018-11-06
dc.date.submitted2018-12-21
dc.identifier.citation<p>Life (Basel). 2018 Nov 6;8(4). pii: life8040057. doi: 10.3390/life8040057. <a href="https://doi.org/10.3390/life8040057">Link to article on publisher's site</a></p>
dc.identifier.issn2075-1729 (Linking)
dc.identifier.doi10.3390/life8040057
dc.identifier.pmid30404133
dc.identifier.urihttp://hdl.handle.net/20.500.14038/40869
dc.description.abstractUnderstanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple feedstocks under prebiotically plausible conditions. It is well established that evolution of life involved RNA which plays central roles in both inheritance and catalysis. In this review, we present historically important and recently published articles aimed at understanding the emergence of RNA nucleosides and nucleotides on the early Earth.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=30404133&dopt=Abstract">Link to Article in PubMed</a></p>
dc.rights© 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectnucleotide and nucleoside synthesis
dc.subjectorigin of life
dc.subjectprebiotic chemistry
dc.subjectBiochemistry
dc.subjectBiology
dc.subjectChemistry
dc.subjectNucleic Acids, Nucleotides, and Nucleosides
dc.titleExploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth
dc.typeJournal Article
dc.source.journaltitleLife (Basel, Switzerland)
dc.source.volume8
dc.source.issue4
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4685&amp;context=oapubs&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/oapubs/3673
dc.identifier.contextkey13525567
refterms.dateFOA2022-08-23T16:46:23Z
html.description.abstract<p>Understanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple feedstocks under prebiotically plausible conditions. It is well established that evolution of life involved RNA which plays central roles in both inheritance and catalysis. In this review, we present historically important and recently published articles aimed at understanding the emergence of RNA nucleosides and nucleotides on the early Earth.</p>
dc.identifier.submissionpathoapubs/3673
dc.contributor.departmentRNA Therapeutics Institute
dc.source.pages57


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© 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).