Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth
dc.contributor.author | Biscans, Annabelle | |
dc.date | 2022-08-11T08:09:51.000 | |
dc.date.accessioned | 2022-08-23T16:46:23Z | |
dc.date.available | 2022-08-23T16:46:23Z | |
dc.date.issued | 2018-11-06 | |
dc.date.submitted | 2018-12-21 | |
dc.identifier.citation | <p>Life (Basel). 2018 Nov 6;8(4). pii: life8040057. doi: 10.3390/life8040057. <a href="https://doi.org/10.3390/life8040057">Link to article on publisher's site</a></p> | |
dc.identifier.issn | 2075-1729 (Linking) | |
dc.identifier.doi | 10.3390/life8040057 | |
dc.identifier.pmid | 30404133 | |
dc.identifier.uri | http://hdl.handle.net/20.500.14038/40869 | |
dc.description.abstract | Understanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple feedstocks under prebiotically plausible conditions. It is well established that evolution of life involved RNA which plays central roles in both inheritance and catalysis. In this review, we present historically important and recently published articles aimed at understanding the emergence of RNA nucleosides and nucleotides on the early Earth. | |
dc.language.iso | en_US | |
dc.relation | <p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=30404133&dopt=Abstract">Link to Article in PubMed</a></p> | |
dc.rights | © 2018 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | nucleotide and nucleoside synthesis | |
dc.subject | origin of life | |
dc.subject | prebiotic chemistry | |
dc.subject | Biochemistry | |
dc.subject | Biology | |
dc.subject | Chemistry | |
dc.subject | Nucleic Acids, Nucleotides, and Nucleosides | |
dc.title | Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth | |
dc.type | Journal Article | |
dc.source.journaltitle | Life (Basel, Switzerland) | |
dc.source.volume | 8 | |
dc.source.issue | 4 | |
dc.identifier.legacyfulltext | https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4685&context=oapubs&unstamped=1 | |
dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/oapubs/3673 | |
dc.identifier.contextkey | 13525567 | |
refterms.dateFOA | 2022-08-23T16:46:23Z | |
html.description.abstract | <p>Understanding how life began is one of the most fascinating problems to solve. By approaching this enigma from a chemistry perspective, the goal is to define what series of chemical reactions could lead to the synthesis of nucleotides, amino acids, lipids, and other cellular components from simple feedstocks under prebiotically plausible conditions. It is well established that evolution of life involved RNA which plays central roles in both inheritance and catalysis. In this review, we present historically important and recently published articles aimed at understanding the emergence of RNA nucleosides and nucleotides on the early Earth.</p> | |
dc.identifier.submissionpath | oapubs/3673 | |
dc.contributor.department | RNA Therapeutics Institute | |
dc.source.pages | 57 |