Authors
Bertoldi, Andrea DamasoChaves, Luisa Arueira
Ross-Degnan, Dennis
Luiza, Vera Lucia
Emmerick, Isabel Cristina Martins
Mendes da Silva, Rondineli
Campos, Monica Rodrigues.
UMass Chan Affiliations
Department of Surgery, Division of Thoracic SurgeryDocument Type
Journal ArticlePublication Date
2019-10-17Keywords
Generic Drugs; Generic Drug Policy; Antihypertensive Agents; Hypoglycemic AgentsHealth Economics
Health Policy
Insurance
Pharmaceutical Preparations
Pharmacoeconomics and Pharmaceutical Economics
Pharmacy Administration, Policy and Regulation
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OBJECTIVE: To evaluate trends in the use of generic and non-generic medicines to treat hypertension and diabetes under the Farmacia Popular Program (FP) and its impact on generic medicines sales volume and market share in the Brazilian pharmaceutical market. METHODS: This longitudinal, retrospective study used interrupted time series design to analyze changes in monthly sales volume and proportion of medicines sales (market share) for oral antidiabetic and antihypertensive medicines for generic versus non-generic products. Analyses were conducted in a combined dataset that aggregate monthly sales volumes from the Farmacia Popular program and from the QuintilesIMS (IQVIA) national market sales data from January 2007 to December 2012. The Farmacia Popular program phases analyzed included: a) 2009 reductions in medicines reference prices (AFP-II) and b) 2011 implementation of free medicines program for hypertension and diabetes, the Saude nao tem preco (SNTP - Health has no price). RESULTS: Patterns of use for FP-covered antidiabetic and antihypertensive medicines were similar to their use in the market in general. After one year of the decreases in government subsidies in April 2010, market share of antidiabetic and antihypertensive medicines experienced relative declines of -54.5% and -59.9%, respectively. However, when FP-covered medicines were made free to patients, overall market volume for antidiabetic and antihypertensive generics increased dramatically, with 242.6% and 277.0% relative increases by February 2012, as well as non-generics with relative increase of 209.7% and 279% for antidiabetic and antihypertensive medicines, respectively. CONCLUSIONS: Ministry of Health policies on the amount of patient cost sharing and on the choice of medicines on coverage lists have substantial impacts on overall generic sales volume in retail pharmacies.Source
Rev Saude Publica. 2019 Oct 17;53:94. doi: 10.11606/s1518-8787.2019053001237. eCollection 2019. Link to article on publisher's site
DOI
10.11606/s1518-8787.2019053001237Permanent Link to this Item
http://hdl.handle.net/20.500.14038/41242PubMed ID
31644724Related Resources
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Copyright: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original author and source are credited.Distribution License
http://creativecommons.org/licenses/by/4.0/ae974a485f413a2113503eed53cd6c53
10.11606/s1518-8787.2019053001237
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Except where otherwise noted, this item's license is described as Copyright: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original author and source are credited.