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Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome

dc.contributor.authorAuld, Sara C.
dc.contributor.authorMaenetje, Pholo
dc.contributor.authorRavimohan, Shruthi
dc.contributor.authorWeissman, Drew
dc.contributor.authorNcube, Itai
dc.contributor.authorMlotshwa, Mandla
dc.contributor.authorRatsela, Nelly
dc.contributor.authorChase, William
dc.contributor.authorVangu, Mboyo-Di-Tamba
dc.contributor.authorWallis, Robert
dc.contributor.authorChurchyard, Gavin
dc.contributor.authorKornfeld, Hardy
dc.contributor.authorBisson, Gregory P.
dc.date2022-08-11T08:09:56.000
dc.date.accessioned2022-08-23T16:49:16Z
dc.date.available2022-08-23T16:49:16Z
dc.date.issued2020-04-10
dc.date.submitted2020-05-08
dc.identifier.citation<p>Auld SC, Maenetje P, Ravimohan S, Weissman D, Ncube I, Mlotshwa M, Ratsela N, Chase W, Vangu MD, Wallis R, Churchyard G, Kornfeld H, Bisson GP. Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome. Clin Infect Dis. 2020 Apr 10;70(8):1750-1753. doi: 10.1093/cid/ciz733. PMID: 31552412; PMCID: PMC7146005. <a href="https://doi.org/10.1093/cid/ciz733">Link to article on publisher's site</a></p>
dc.identifier.issn1058-4838 (Linking)
dc.identifier.doi10.1093/cid/ciz733
dc.identifier.pmid31552412
dc.identifier.urihttp://hdl.handle.net/20.500.14038/41427
dc.description.abstractEnd-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral therapy, suggesting a role for lung function in TB-IRIS definitions.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=31552412&dopt=Abstract">Link to Article in PubMed</a></p>
dc.rights© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectHIV
dc.subjectimmune reconstitution inflammatory syndrome
dc.subjectpulmonary function
dc.subjecttuberculosis
dc.subjectBacterial Infections and Mycoses
dc.subjectInfectious Disease
dc.subjectPulmonology
dc.subjectRespiratory Tract Diseases
dc.subjectVirus Diseases
dc.subjectViruses
dc.titleDeclines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
dc.typeJournal Article
dc.source.journaltitleClinical infectious diseases : an official publication of the Infectious Diseases Society of America
dc.source.volume70
dc.source.issue8
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=5227&amp;context=oapubs&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/oapubs/4208
dc.identifier.contextkey17677184
refterms.dateFOA2022-08-23T16:49:16Z
html.description.abstract<p>End-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral therapy, suggesting a role for lung function in TB-IRIS definitions.</p>
dc.identifier.submissionpathoapubs/4208
dc.contributor.departmentDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine
dc.source.pages1750-1753


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© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Except where otherwise noted, this item's license is described as © The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com