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dc.contributor.authorKuban, Karl C.K.
dc.contributor.authorAllred, Elizabeth N.
dc.contributor.authorO'Shea, Michael A.
dc.contributor.authorPaneth, Nigel
dc.contributor.authorPagano, Marcello
dc.contributor.authorLeviton, Alan
dc.contributor.authorELGAN Study Cerebral Palsy-Algorithm Group
dc.contributor.authorBream, Richard
dc.contributor.authorAdair, Robin
dc.contributor.authorMiller, Alice
dc.date2022-08-11T08:10:09.000
dc.date.accessioned2022-08-23T16:57:31Z
dc.date.available2022-08-23T16:57:31Z
dc.date.issued2008-10-07
dc.date.submitted2012-03-05
dc.identifier.citationJ Pediatr. 2008 Oct;153(4):466-72. Epub 2008 Jun 2. <a href="http://dx.doi.org/10.1016/j.jpeds.2008.04.013">Link to article on publisher's site</a>
dc.identifier.issn0022-3476 (Linking)
dc.identifier.doi10.1016/j.jpeds.2008.04.013
dc.identifier.pmid18534210
dc.identifier.urihttp://hdl.handle.net/20.500.14038/43163
dc.description<p>Richard Bream, Robin Adair, and Alice Miller are members of the ELGAN Study Cerebral Palsy-Algorithm Group.</p>
dc.description.abstractOBJECTIVE: To develop an algorithm on the basis of data obtained with a reliable, standardized neurological examination and report the prevalence of cerebral palsy (CP) subtypes (diparesis, hemiparesis, and quadriparesis) in a cohort of 2-year-old children born before 28 weeks gestation. STUDY DESIGN: We compared children with CP subtypes on extent of handicap and frequency of microcephaly, cognitive impairment, and screening positive for autism. RESULTS: Of the 1056 children examined, 11.4% (120) were given an algorithm-based classification of CP. Of these children, 31% had diparesis, 17% had hemiparesis, and 52% had quadriparesis. Children with quadriparesis were 9 times more likely than children with diparesis (76% versus 8%) to be more highly impaired and 5 times more likely than children with diparesis to be microcephalic (43% versus 8%). They were more than twice as likely as children with diparesis to have a score <70 on the mental scale of the BSID-II>(75% versus 34%) and had the highest rate of the Modified Checklist for Autism in Toddlers positivity (76%) compared with children with diparesis (30%) and children without CP (18%). CONCLUSION: We developed an algorithm that classifies CP subtypes, which should permit comparison among studies. Extent of gross motor dysfunction and rates of co-morbidities are highest in children with quadriparesis and lowest in children with diparesis.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=18534210&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581842/pdf/nihms71555.pdf
dc.subject*Algorithms
dc.subjectCD-ROM
dc.subjectCerebral Palsy
dc.subjectChild, Preschool
dc.subjectComorbidity
dc.subjectHemiplegia
dc.subjectHumans
dc.subjectMicrocephaly
dc.subjectNeurologic Examination
dc.subjectPrevalence
dc.subjectQuadriplegia
dc.subjectPediatrics
dc.titleAn algorithm for identifying and classifying cerebral palsy in young children
dc.typeArticle
dc.source.journaltitleThe Journal of pediatrics
dc.source.volume153
dc.source.issue4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/peds_devbeh/10
dc.identifier.contextkey2630034
html.description.abstract<p>OBJECTIVE: To develop an algorithm on the basis of data obtained with a reliable, standardized neurological examination and report the prevalence of cerebral palsy (CP) subtypes (diparesis, hemiparesis, and quadriparesis) in a cohort of 2-year-old children born before 28 weeks gestation.</p> <p>STUDY DESIGN: We compared children with CP subtypes on extent of handicap and frequency of microcephaly, cognitive impairment, and screening positive for autism.</p> <p>RESULTS: Of the 1056 children examined, 11.4% (120) were given an algorithm-based classification of CP. Of these children, 31% had diparesis, 17% had hemiparesis, and 52% had quadriparesis. Children with quadriparesis were 9 times more likely than children with diparesis (76% versus 8%) to be more highly impaired and 5 times more likely than children with diparesis to be microcephalic (43% versus 8%). They were more than twice as likely as children with diparesis to have a score <70 on the mental scale of the BSID-II>(75% versus 34%) and had the highest rate of the Modified Checklist for Autism in Toddlers positivity (76%) compared with children with diparesis (30%) and children without CP (18%).</p> <p>CONCLUSION: We developed an algorithm that classifies CP subtypes, which should permit comparison among studies. Extent of gross motor dysfunction and rates of co-morbidities are highest in children with quadriparesis and lowest in children with diparesis.</p>
dc.identifier.submissionpathpeds_devbeh/10
dc.contributor.departmentDepartment of Pediatrics
dc.source.pages466-72


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