An algorithm for identifying and classifying cerebral palsy in young children
dc.contributor.author | Kuban, Karl C.K. | |
dc.contributor.author | Allred, Elizabeth N. | |
dc.contributor.author | O'Shea, Michael A. | |
dc.contributor.author | Paneth, Nigel | |
dc.contributor.author | Pagano, Marcello | |
dc.contributor.author | Leviton, Alan | |
dc.contributor.author | ELGAN Study Cerebral Palsy-Algorithm Group | |
dc.contributor.author | Bream, Richard | |
dc.contributor.author | Adair, Robin | |
dc.contributor.author | Miller, Alice | |
dc.date | 2022-08-11T08:10:09.000 | |
dc.date.accessioned | 2022-08-23T16:57:31Z | |
dc.date.available | 2022-08-23T16:57:31Z | |
dc.date.issued | 2008-10-07 | |
dc.date.submitted | 2012-03-05 | |
dc.identifier.citation | J Pediatr. 2008 Oct;153(4):466-72. Epub 2008 Jun 2. <a href="http://dx.doi.org/10.1016/j.jpeds.2008.04.013">Link to article on publisher's site</a> | |
dc.identifier.issn | 0022-3476 (Linking) | |
dc.identifier.doi | 10.1016/j.jpeds.2008.04.013 | |
dc.identifier.pmid | 18534210 | |
dc.identifier.uri | http://hdl.handle.net/20.500.14038/43163 | |
dc.description | <p>Richard Bream, Robin Adair, and Alice Miller are members of the ELGAN Study Cerebral Palsy-Algorithm Group.</p> | |
dc.description.abstract | OBJECTIVE: To develop an algorithm on the basis of data obtained with a reliable, standardized neurological examination and report the prevalence of cerebral palsy (CP) subtypes (diparesis, hemiparesis, and quadriparesis) in a cohort of 2-year-old children born before 28 weeks gestation. STUDY DESIGN: We compared children with CP subtypes on extent of handicap and frequency of microcephaly, cognitive impairment, and screening positive for autism. RESULTS: Of the 1056 children examined, 11.4% (120) were given an algorithm-based classification of CP. Of these children, 31% had diparesis, 17% had hemiparesis, and 52% had quadriparesis. Children with quadriparesis were 9 times more likely than children with diparesis (76% versus 8%) to be more highly impaired and 5 times more likely than children with diparesis to be microcephalic (43% versus 8%). They were more than twice as likely as children with diparesis to have a score <70 on the mental scale of the BSID-II>(75% versus 34%) and had the highest rate of the Modified Checklist for Autism in Toddlers positivity (76%) compared with children with diparesis (30%) and children without CP (18%). CONCLUSION: We developed an algorithm that classifies CP subtypes, which should permit comparison among studies. Extent of gross motor dysfunction and rates of co-morbidities are highest in children with quadriparesis and lowest in children with diparesis. | |
dc.language.iso | en_US | |
dc.relation | <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=18534210&dopt=Abstract">Link to Article in PubMed</a> | |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581842/pdf/nihms71555.pdf | |
dc.subject | *Algorithms | |
dc.subject | CD-ROM | |
dc.subject | Cerebral Palsy | |
dc.subject | Child, Preschool | |
dc.subject | Comorbidity | |
dc.subject | Hemiplegia | |
dc.subject | Humans | |
dc.subject | Microcephaly | |
dc.subject | Neurologic Examination | |
dc.subject | Prevalence | |
dc.subject | Quadriplegia | |
dc.subject | Pediatrics | |
dc.title | An algorithm for identifying and classifying cerebral palsy in young children | |
dc.type | Journal Article | |
dc.source.journaltitle | The Journal of pediatrics | |
dc.source.volume | 153 | |
dc.source.issue | 4 | |
dc.identifier.legacycoverpage | https://escholarship.umassmed.edu/peds_devbeh/10 | |
dc.identifier.contextkey | 2630034 | |
html.description.abstract | <p>OBJECTIVE: To develop an algorithm on the basis of data obtained with a reliable, standardized neurological examination and report the prevalence of cerebral palsy (CP) subtypes (diparesis, hemiparesis, and quadriparesis) in a cohort of 2-year-old children born before 28 weeks gestation.</p> <p>STUDY DESIGN: We compared children with CP subtypes on extent of handicap and frequency of microcephaly, cognitive impairment, and screening positive for autism.</p> <p>RESULTS: Of the 1056 children examined, 11.4% (120) were given an algorithm-based classification of CP. Of these children, 31% had diparesis, 17% had hemiparesis, and 52% had quadriparesis. Children with quadriparesis were 9 times more likely than children with diparesis (76% versus 8%) to be more highly impaired and 5 times more likely than children with diparesis to be microcephalic (43% versus 8%). They were more than twice as likely as children with diparesis to have a score <70 on the mental scale of the BSID-II>(75% versus 34%) and had the highest rate of the Modified Checklist for Autism in Toddlers positivity (76%) compared with children with diparesis (30%) and children without CP (18%).</p> <p>CONCLUSION: We developed an algorithm that classifies CP subtypes, which should permit comparison among studies. Extent of gross motor dysfunction and rates of co-morbidities are highest in children with quadriparesis and lowest in children with diparesis.</p> | |
dc.identifier.submissionpath | peds_devbeh/10 | |
dc.contributor.department | Department of Pediatrics | |
dc.source.pages | 466-72 |