AuthorsSerebruany, Victor L.
Oshrine, Benjamin R.
Malinin, Alex I.
Michelson, Alan D.
Ferguson, James J. III
UMass Chan AffiliationsDepartment of Pediatrics
Clinical Trials as Topic
MetadataShow full item record
AbstractThis article reviews the current literature on attempts to improve compliance and the effect of NC on clinical trials, with a focus on cardiovascular trials (and antiplatelet therapy in particular). Compliance is a major concern for physicians and researchers not only because of its overwhelming financial impact on health care and its potential to undermine clinical outcomes, but also because it poses critical questions about the validity of results from clinical trials. Understanding the implications of NC in practice and research will serve to improve future clinical trial design to accommodate the confounding aspects associated with NC.
SourceAm Heart J. 2005 Nov;150(5):882-6. doi: 10.1016/j.ahj.2005.02.039
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/43394
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