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dc.contributor.authorBlake, Diane R.
dc.contributor.authorSpielberg, Freya
dc.contributor.authorLevy, Vivian
dc.contributor.authorLensing, Shelly
dc.contributor.authorWolff, Peter A.
dc.contributor.authorVenkatasubramanian, Lalitha
dc.contributor.authorAcevedo, Nincoshka
dc.contributor.authorPadian, Nancy
dc.contributor.authorChattopadhyay, Ishita
dc.contributor.authorGaydos, Charlotte A.
dc.date2022-08-11T08:10:13.000
dc.date.accessioned2022-08-23T17:00:04Z
dc.date.available2022-08-23T17:00:04Z
dc.date.issued2015-01-01
dc.date.submitted2016-10-28
dc.identifier.citationSex Transm Dis. 2015 Jan;42(1):13-9. doi: 10.1097/OLQ.0000000000000221. <a href="http://dx.doi.org/10.1097/OLQ.0000000000000221">Link to article on publisher's site</a>
dc.identifier.issn0148-5717 (Linking)
dc.identifier.doi10.1097/OLQ.0000000000000221
dc.identifier.pmid25504295
dc.identifier.urihttp://hdl.handle.net/20.500.14038/43725
dc.description.abstractBACKGROUND: Results of a recent demonstration project evaluating feasibility, acceptability, and cost of a Web-based sexually transmitted infection (STI) testing and e-prescription treatment program (eSTI) suggest that this approach could be a feasible alternative to clinic-based testing and treatment, but the results need to be confirmed by a randomized comparative effectiveness trial. METHODS: We modeled a decision tree comparing (1) cost of eSTI screening using a home collection kit and an e-prescription for uncomplicated treatment versus (2) hypothetical costs derived from the literature for referral to standard clinic-based STI screening and treatment. Primary outcome was number of STIs detected. Analyses were conducted from the clinical trial perspective and the health care system perspective. RESULTS: The eSTI strategy detected 75 infections, and the clinic referral strategy detected 45 infections. Total cost of eSTI was $94,938 ($1266/STI detected) from the clinical trial perspective and $96,088 ($1281/STI detected) from the health care system perspective. Total cost of clinic referral was $87,367 ($1941/STI detected) from the clinical trial perspective and $71,668 ($1593/STI detected) from the health care system perspective. CONCLUSIONS: Results indicate that eSTI will likely be more cost-effective (lower cost/STI detected) than clinic-based STI screening, both in the context of clinical trials and in routine clinical care. Although our results are promising, they are based on a demonstration project and estimates from other small studies. A comparative effectiveness research trial is needed to determine actual cost and impact of the eSTI system on identification and treatment of new infections and prevention of their sequelae.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=25504295&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276035/
dc.subjectBacterial Infections and Mycoses
dc.subjectFemale Urogenital Diseases and Pregnancy Complications
dc.subjectHealth Services Administration
dc.subjectInfectious Disease
dc.subjectMale Urogenital Diseases
dc.subjectPediatrics
dc.titleCould home sexually transmitted infection specimen collection with e-prescription be a cost-effective strategy for clinical trials and clinical care
dc.typeArticle
dc.source.journaltitleSexually transmitted diseases
dc.source.volume42
dc.source.issue1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/peds_pp/38
dc.identifier.contextkey9320391
html.description.abstract<p>BACKGROUND: Results of a recent demonstration project evaluating feasibility, acceptability, and cost of a Web-based sexually transmitted infection (STI) testing and e-prescription treatment program (eSTI) suggest that this approach could be a feasible alternative to clinic-based testing and treatment, but the results need to be confirmed by a randomized comparative effectiveness trial.</p> <p>METHODS: We modeled a decision tree comparing (1) cost of eSTI screening using a home collection kit and an e-prescription for uncomplicated treatment versus (2) hypothetical costs derived from the literature for referral to standard clinic-based STI screening and treatment. Primary outcome was number of STIs detected. Analyses were conducted from the clinical trial perspective and the health care system perspective.</p> <p>RESULTS: The eSTI strategy detected 75 infections, and the clinic referral strategy detected 45 infections. Total cost of eSTI was $94,938 ($1266/STI detected) from the clinical trial perspective and $96,088 ($1281/STI detected) from the health care system perspective. Total cost of clinic referral was $87,367 ($1941/STI detected) from the clinical trial perspective and $71,668 ($1593/STI detected) from the health care system perspective.</p> <p>CONCLUSIONS: Results indicate that eSTI will likely be more cost-effective (lower cost/STI detected) than clinic-based STI screening, both in the context of clinical trials and in routine clinical care. Although our results are promising, they are based on a demonstration project and estimates from other small studies. A comparative effectiveness research trial is needed to determine actual cost and impact of the eSTI system on identification and treatment of new infections and prevention of their sequelae.</p>
dc.identifier.submissionpathpeds_pp/38
dc.contributor.departmentDepartment of Pediatrics, Division of Adolescent Medicine
dc.source.pages13-9


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