A mechanical basis for chromosome function
UMass Chan Affiliations
Program in Gene Function and ExpressionDocument Type
Journal ArticlePublication Date
2004-08-24Keywords
AnimalsChromatin
Chromosomes
DNA, Plant
Humans
Meiosis
Mitosis
Models, Biological
Nucleic Acid Conformation
Stress, MechanicalTime FactorsGenetics and Genomics
Metadata
Show full item recordAbstract
We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.Source
Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12592-7. Epub 2004 Aug 6. Link to article on publisher's site
DOI
10.1073/pnas.0402724101Permanent Link to this Item
http://hdl.handle.net/20.500.14038/43928PubMed ID
15299144Related Resources
Link to Article in PubMedRights
Copyright © 2004, The National Academy of Sciences
Publisher PDF posted as allowed by the publisher's author rights policy at http://www.pnas.org/site/misc/authorfaq.shtml.