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A mechanical basis for chromosome function

dc.contributor.authorKleckner, Nancy
dc.contributor.authorZickler, Denise
dc.contributor.authorJones, Gareth H.
dc.contributor.authorDekker, Job
dc.contributor.authorPadmore, Ruth
dc.contributor.authorHenle, Jim
dc.contributor.authorHutchinson, John N.
dc.date2022-08-11T08:10:15.000
dc.date.accessioned2022-08-23T17:01:04Z
dc.date.available2022-08-23T17:01:04Z
dc.date.issued2004-08-24
dc.date.submitted2011-04-19
dc.identifier.citation<p>Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12592-7. Epub 2004 Aug 6. <a href="http://dx.doi.org/10.1073/pnas.0402724101" target="_blank">Link to article on publisher's site</a></p>
dc.identifier.issn0027-8424 (Linking)
dc.identifier.doi10.1073/pnas.0402724101
dc.identifier.pmid15299144
dc.identifier.urihttp://hdl.handle.net/20.500.14038/43928
dc.description.abstractWe propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=15299144&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1073/pnas.0402724101
dc.rights<p>Copyright © 2004, The National Academy of Sciences</p> <p>Publisher PDF posted as allowed by the publisher's author rights policy at http://www.pnas.org/site/misc/authorfaq.shtml.</p>
dc.subjectAnimals
dc.subjectChromatin
dc.subjectChromosomes
dc.subjectDNA, Plant
dc.subjectHumans
dc.subjectMeiosis
dc.subjectMitosis
dc.subjectModels, Biological
dc.subjectNucleic Acid Conformation
dc.subjectStress, Mechanical
dc.subjectTime Factors
dc.subjectGenetics and Genomics
dc.titleA mechanical basis for chromosome function
dc.typeJournal Article
dc.source.journaltitleProceedings of the National Academy of Sciences of the United States of America
dc.source.volume101
dc.source.issue34
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1139&amp;context=pgfe_pp&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/pgfe_pp/139
dc.identifier.contextkey1946794
refterms.dateFOA2022-08-23T17:01:04Z
html.description.abstract<p>We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.</p>
dc.identifier.submissionpathpgfe_pp/139
dc.contributor.departmentProgram in Gene Function and Expression
dc.source.pages12592-7


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