AuthorsMeyers, Richard M.
ENCODE Project Consortium
Lajoie, Bryan R.
Whitfield, Troy W.
UMass Chan AffiliationsProgram in Bioinformatics and Integrative Biology
Program in Gene Function and Expression
MetadataShow full item record
AbstractThe mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the scientific and medical communities to interpret the human genome sequence and apply it to understand human biology and improve health. The ENCODE Consortium is integrating multiple technologies and approaches in a collective effort to discover and define the functional elements encoded in the human genome, including genes, transcripts, and transcriptional regulatory regions, together with their attendant chromatin states and DNA methylation patterns. In the process, standards to ensure high-quality data have been implemented, and novel algorithms have been developed to facilitate analysis. Data and derived results are made available through a freely accessible database. Here we provide an overview of the project and the resources it is generating and illustrate the application of ENCODE data to interpret the human genome.
SourceThe ENCODE Project Consortium (2011) A User's Guide to the Encyclopedia of DNA Elements (ENCODE). PLoS Biol 9(4): e1001046. doi:10.1371/journal.pbio.1001046. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/43949
Job Dekker, Bryan R. Lajoie, Amartya Sanyal, Zhiping Weng, Troy W. Whitfield, and Jie Wang are members of The ENCODE Project Consortium.
Related ResourcesLink to Article in PubMed