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Chromatin-mediated Candida albicans virulence

dc.contributor.authorLopes da Rosa, Jessica
dc.contributor.authorKaufman, Paul D.
dc.date2022-08-11T08:10:15.000
dc.date.accessioned2022-08-23T17:01:31Z
dc.date.available2022-08-23T17:01:31Z
dc.date.issued2012-01-01
dc.date.submitted2014-03-20
dc.identifier.citationJessica Lopes da Rosa, Paul D. Kaufman, Chromatin-mediated Candida albicans virulence, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Volume 1819, Issues 3–4, March–April 2012, Pages 349-355, http://dx.doi.org/10.1016/j.bbagrm.2011.08.007.
dc.identifier.issn0006-3002 (Linking)
dc.identifier.doi10.1016/j.bbagrm.2011.08.007
dc.identifier.pmid24459737
dc.identifier.urihttp://hdl.handle.net/20.500.14038/44024
dc.description<p>First author Jessica Lopes da Rosa is a doctoral student in the Interdisciplinary Graduate Program in the Graduate School of Biomedical Sciences (GSBS) at UMass Medical School.</p>
dc.description.abstractCandida albicans is the most prevalent human fungal pathogen. To successfully propagate an infection, this organism relies on the ability to change morphology, express virulence-associated genes and resist DNA damage caused by the host immune system. Many of these events involve chromatin alterations that are crucial for virulence. This review will focus on the studies that have been conducted on how chromatin function affects pathogenicity of C. albicans and other fungi. This article is part of a Special Issue entitled: Histone chaperones and Chromatin assembly.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=24459737&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1016/j.bbagrm.2011.08.007
dc.subjectCandida albicans
dc.subjectCandidiasis
dc.subjectChromatin
dc.subjectDNA Repair
dc.subjectGenomic Instability
dc.subjectHost-Pathogen Interactions
dc.subjectHumans
dc.subjectTranscription, Genetic
dc.subjectVirulence
dc.subjectCandida albicans
dc.subjectRtt109
dc.subjectHistone H3 lysine 56
dc.subjectChromatin modification
dc.subjectDNA damage
dc.subjectFungal pathogen
dc.subjectBiochemistry
dc.subjectGenetics and Genomics
dc.subjectImmunopathology
dc.subjectPathogenic Microbiology
dc.titleChromatin-mediated Candida albicans virulence
dc.typeJournal Article
dc.source.journaltitleBiochimica et biophysica acta
dc.source.volume1819
dc.source.issue3-4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/pgfe_pp/238
dc.identifier.contextkey5362386
html.description.abstract<p>Candida albicans is the most prevalent human fungal pathogen. To successfully propagate an infection, this organism relies on the ability to change morphology, express virulence-associated genes and resist DNA damage caused by the host immune system. Many of these events involve chromatin alterations that are crucial for virulence. This review will focus on the studies that have been conducted on how chromatin function affects pathogenicity of C. albicans and other fungi. This article is part of a Special Issue entitled: Histone chaperones and Chromatin assembly.</p>
dc.identifier.submissionpathpgfe_pp/238
dc.contributor.departmentProgram in Gene Function and Expression
dc.source.pages349-55


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