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FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system

dc.contributor.authorZhu, Lihua Julie
dc.contributor.authorChristensen, Ryan G.
dc.contributor.authorKazemian, Majid
dc.contributor.authorHull, Christopher J.
dc.contributor.authorEnuameh, Metewo Selase
dc.contributor.authorBasciotta, Matthew D.
dc.contributor.authorBrasefield, Jessie A.
dc.contributor.authorZhu, Cong
dc.contributor.authorAsriyan, Yuna
dc.contributor.authorLapointe, David S.
dc.contributor.authorSinha, Saurabh
dc.contributor.authorWolfe, Scot A.
dc.contributor.authorBrodsky, Michael H.
dc.date2022-08-11T08:10:16.000
dc.date.accessioned2022-08-23T17:01:42Z
dc.date.available2022-08-23T17:01:42Z
dc.date.issued2011-01-26
dc.date.submitted2011-04-19
dc.identifier.citationNucleic Acids Res. 2011 Jan;39(Database issue):D111-7. Epub 2010 Nov 19. <a href="http://dx.doi.org/10.1093/nar/gkq858">Link to article on publisher's site</a>
dc.identifier.issn0305-1048 (Linking)
dc.identifier.doi10.1093/nar/gkq858
dc.identifier.pmid21097781
dc.identifier.urihttp://hdl.handle.net/20.500.14038/44061
dc.description.abstractFlyFactorSurvey (http://pgfe.umassmed.edu/TFDBS/) is a database of DNA binding specificities for Drosophila transcription factors (TFs) primarily determined using the bacterial one-hybrid system. The database provides community access to over 400 recognition motifs and position weight matrices for over 200 TFs, including many unpublished motifs. Search tools and flat file downloads are provided to retrieve binding site information (as sequences, matrices and sequence logos) for individual TFs, groups of TFs or for all TFs with characterized binding specificities. Linked analysis tools allow users to identify motifs within our database that share similarity to a query matrix or to view the distribution of occurrences of an individual motif throughout the Drosophila genome. Together, this database and its associated tools provide computational and experimental biologists with resources to predict interactions between Drosophila TFs and target cis-regulatory sequences.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=21097781&dopt=Abstract">Link to Article in PubMed</a>
dc.subjectDNA-Binding Proteins
dc.subjectDrosophila Proteins
dc.subjectTranscription Factors
dc.subjectDatabases, Protein
dc.subjectProtein Interaction Domains and Motifs
dc.subjectGenetics and Genomics
dc.titleFlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
dc.typeJournal Article
dc.source.journaltitleNucleic acids research
dc.source.volume39
dc.source.issueDatabase issue
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1037&amp;context=pgfe_pp&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/pgfe_pp/37
dc.identifier.contextkey1946690
refterms.dateFOA2022-08-23T17:01:42Z
html.description.abstract<p>FlyFactorSurvey (http://pgfe.umassmed.edu/TFDBS/) is a database of DNA binding specificities for Drosophila transcription factors (TFs) primarily determined using the bacterial one-hybrid system. The database provides community access to over 400 recognition motifs and position weight matrices for over 200 TFs, including many unpublished motifs. Search tools and flat file downloads are provided to retrieve binding site information (as sequences, matrices and sequence logos) for individual TFs, groups of TFs or for all TFs with characterized binding specificities. Linked analysis tools allow users to identify motifs within our database that share similarity to a query matrix or to view the distribution of occurrences of an individual motif throughout the Drosophila genome. Together, this database and its associated tools provide computational and experimental biologists with resources to predict interactions between Drosophila TFs and target cis-regulatory sequences.</p>
dc.identifier.submissionpathpgfe_pp/37
dc.contributor.departmentDepartment of Biochemistry and Molecular Pharmacology
dc.contributor.departmentProgram in Molecular Medicine
dc.contributor.departmentInformation Services
dc.contributor.departmentProgram in Gene Function and Expression
dc.source.pagesD111-7


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