Evaluation of the American Heart Association cardiovascular disease prevention guideline for women
Authors
Hsia, JudithRodabough, Rebecca J
Manson, JoAnn E.
Liu, Simin
Freiberg, Matthew S.
Graettinger, William
Rosal, Milagros C.
Cochrane, Barb
Lloyd-Jones, Donald
Robinson, Jennifer G.
Howard, Barbara V.
Women’s Health Initiative Research Group
UMass Chan Affiliations
Department of Medicine, Division of Preventive and Behavioral MedicineDocument Type
Journal ArticlePublication Date
2010-03-01Keywords
AgedAlgorithms
*American Heart Association
Cardiovascular Diseases
control
Chi-Square Distribution
Female
Follow-Up Studies
Humans
Life Style
Logistic Models
Middle Aged
*Practice Guidelines as Topic
Prognosis
Proportional Hazards Models
Prospective Studies
ROC Curve
Risk Assessment
Risk Factors
Sex Factors
Time Factors
United States
*Women's Health
*Women's Health Services
Behavior and Behavior Mechanisms
Cardiovascular Diseases
Community Health
Community Health and Preventive Medicine
Public Health
Public Health Education and Promotion
Women's Health
Metadata
Show full item recordAbstract
BACKGROUND: The 2007 update to the American Heart Association (AHA) guidelines for cardiovascular disease prevention in women recommend a simplified approach to risk stratification. We assigned Women's Health Initiative participants to risk categories as described in the guideline and evaluated clinical event rates within and between strata. METHODS AND RESULTS: The Women's Health Initiative enrolled 161 808 women ages 50 to 79 years and followed them prospectively for 7.8 years (mean). Applying the 2007 AHA guideline categories, 11% of women were high risk, 72% at-risk, and 4% at optimal risk; 13% of women did not fall into any category, that is, lacked risk factors but did not adhere to a healthy lifestyle (moderate intensity exercise for 30 minute most days and 20% (area under receiver operating characteristic curve for Framingham risk, 0.724; for AHA risk, 0.664; P<0.0001). CONCLUSIONS: Risk stratification as proposed in the 2007 AHA guideline is simple, accessible to patients and providers, and identifies cardiovascular risk with accuracy similar to that of the current Framingham algorithm. Clinical Trial Registration- clinicaltrials.gov. Identifier: NCT00000611.Source
Hsia J, Rodabough RJ, Manson JE, Liu S, Freiberg MS, Graettinger W, Rosal MC, Cochrane B, Lloyd-Jones D, Robinson JG, Howard BV; Women's Health Initiative Research Group. Evaluation of the American Heart Association cardiovascular disease prevention guideline for women. Circ Cardiovasc Qual Outcomes. 2010 Mar;3(2):128-34. doi: 10.1161/CIRCOUTCOMES.108.842385. Link to article on publisher's siteDOI
10.1161/CIRCOUTCOMES.108.842385Permanent Link to this Item
http://hdl.handle.net/20.500.14038/44545PubMed ID
20160160Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1161/CIRCOUTCOMES.108.842385
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