Association of past and recent major depression and menstrual characteristics in midlife: Study of Women's Health Across the Nation
Authors
Bromberger, Joyce T.Schott, Laura L.
Matthews, Karen A.
Kravitz, Howard M.
Randolph, John F. Jr.
Harlow, Sioban D.
Crawford, Sybil L.
Green, Robin
Joffe, Hadine
UMass Chan Affiliations
Department of Medicine, Division of Preventive and Behavioral MedicineDocument Type
Journal ArticlePublication Date
2012-09-01Keywords
MenstruationDepression
Community Health and Preventive Medicine
Mental and Social Health
Obstetrics and Gynecology
Preventive Medicine
Psychiatry
Metadata
Show full item recordAbstract
OBJECTIVE: The aim of this study was to examine the association of a history of major depression (MD) with menstrual problems in a multiethnic sample of midlife women. METHODS: Participants were 934 women enrolled in the Study of Women's Health Across the Nation, a multisite study of menopause and aging. The outcomes were menstrual bleeding problems and premenstrual symptoms in the year before study entry. The Structured Clinical Interview for the Diagnosis of DSM-IV Axis I Disorders was conducted to determine recent and past psychiatric diagnoses. Covariates included sociodemographic, behavioral, and gynecologic factors. RESULTS: One third of the participants reported heavy bleeding, 20% reported other abnormal bleeding, and 18% reported premenstrual symptoms. One third had past and 11% had recent MD. Past MD was associated with an increased likelihood of heavy bleeding (odds ratio, 1.89; 95% CI, 1.25-2.85), adjusting for recent MD, menopause status, and other covariates. Past MD was not associated with other abnormal bleeding or premenstrual symptoms in the final analysis that adjusted for recent MD. CONCLUSIONS: Midlife women with a history of MD are more likely to report heavy bleeding.Source
Menopause. 2012 Sep;19(9):959-966. Link to article on publisher's siteDOI
10.1097/gme.0b013e318248f2d5Permanent Link to this Item
http://hdl.handle.net/20.500.14038/44813PubMed ID
22510936Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1097/gme.0b013e318248f2d5