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    Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Process, format, and clinimetric testing plan

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    Authors
    Goetz, Christopher
    Fahn, Stanley
    Martinez-Martin, Pablo
    Poewe, Werner
    Sampaio, Cristina
    Stebbins, Glenn T.
    Stern, Matthew B.
    Tilley, Barbara C.
    Dodel, Richard
    Dubois, Bruno
    Holloway, Robert
    Jankovic, Joseph
    Kulisevsky, Jaime
    Lang, Anthony E.
    Lees, Andrew
    Leurgans, Sue
    LeWitt, Peter A.
    Nyenhuis, David
    Olanow, C. Warren
    Rascol, Olivier
    Schrag, Anette
    Teresi, Jeanne A.
    van Hilten, Jacobus J.
    LaPelle, Nancy R.
    Show allShow less
    UMass Chan Affiliations
    Department of Medicine, Division of Preventive and Behavioral Medicine
    Document Type
    Journal Article
    Publication Date
    2007-01-01
    Keywords
    *Disability Evaluation
    Humans
    Movement Disorders
    Parkinson Disease
    *Psychometrics
    Questionnaires
    Reproducibility of Results
    Severity of Illness Index
    Nervous System Diseases
    
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    Link to Full Text
    http://dx.doi.org/10.1002/mds.21198
    Abstract
    This article presents the revision process, major innovations, and clinimetric testing program for the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (UPDRS), known as the MDS-UPDRS. The UPDRS is the most widely used scale for the clinical study of Parkinson's disease (PD). The MDS previously organized a critique of the UPDRS, which cited many strengths, but recommended revision of the scale to accommodate new advances and to resolve problematic areas. An MDS-UPDRS committee prepared the revision using the recommendations of the published critique of the scale. Subcommittees developed new material that was reviewed by the entire committee. A 1-day face-to-face committee meeting was organized to resolve areas of debate and to arrive at a working draft ready for clinimetric testing. The MDS-UPDRS retains the UPDRS structure of four parts with a total summed score, but the parts have been modified to provide a section that integrates nonmotor elements of PD: I, Nonmotor Experiences of Daily Living; II, Motor Experiences of Daily Living; III, Motor Examination; and IV, Motor Complications. All items have five response options with uniform anchors of 0 = normal, 1 = slight, 2 = mild, 3 = moderate, and 4 = severe. Several questions in Part I and all of Part II are written as a patient/caregiver questionnaire, so that the total rater time should remain approximately 30 minutes. Detailed instructions for testing and data acquisition accompany the MDS-UPDRS in order to increase uniform usage. Multiple language editions are planned. A three-part clinimetric program will provide testing of reliability, validity, and responsiveness to interventions. Although the MDS-UPDRS will not be published until it has successfully passed clinimetric testing, explanation of the process, key changes, and clinimetric programs allow clinicians and researchers to understand and participate in the revision process.
    Source
    Mov Disord. 2007 Jan;22(1):41-7. Link to article on publisher's site
    DOI
    10.1002/mds.21198
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/44835
    PubMed ID
    17115387
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1002/mds.21198
    Scopus Count
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    Population and Quantitative Health Sciences Publications

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