Influence of donor cocaine use on outcome after cardiac transplantation: analysis of the United Network for Organ Sharing Thoracic Registry
Rocha, Michael J.
Patten, Richard D.
Konstam, Marvin A.
Patel, Ayan R.
Udelson, James E.
UMass Chan AffiliationsDepartment of Medicine, Division of Preventive and Behavioral Medicine
Proportional Hazards Models
Substance Abuse and Addiction
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AbstractHeart transplantation from donors with a history of cocaine abuse remains controversial. Therefore, we examined the consequence of donor cocaine-use history on all-cause mortality and the development of coronary artery disease after heart transplantation. Using the United Network for Organ Sharing Thoracic Registry we identified 9,217 first-time heart-only adult transplant recipients between January 1999 and December 2003, and then divided this cohort into sub-groups based on the reported history of donor cocaine use. Multivariate analysis revealed no difference in mortality or development of coronary artery disease at 1 and 5 years between transplant recipients who received an organ from donors with a history of cocaine use when compared with donors having no history of cocaine use.
SourceBrieke A, Krishnamani R, Rocha MJ, Li W, Patten RD, Konstam MA, Patel AR, Udelson JE, Denofrio D. Influence of donor cocaine use on outcome after cardiac transplantation: analysis of the United Network for Organ Sharing Thoracic Registry. J Heart Lung Transplant. 2008 Dec;27(12):1350-2. doi:10.1016/j.healun.2008.08.008. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/44871
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