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dc.contributor.authorSingh, Inderpal
dc.contributor.authorLi, Wenjun
dc.contributor.authorWoods, Margo
dc.contributor.authorCarville, Angela
dc.contributor.authorTzipori, Saul
dc.date2022-08-11T08:10:21.000
dc.date.accessioned2022-08-23T17:05:31Z
dc.date.available2022-08-23T17:05:31Z
dc.date.issued2006-12-12
dc.date.submitted2014-06-03
dc.identifier.citationJ Med Primatol. 2006 Dec;35(6):352-60. <a href="http://dx.doi.org/10.1111/j.1600-0684.2006.00181.x">Link to article on publisher's site</a>
dc.identifier.issn0047-2565 (Linking)
dc.identifier.doi10.1111/j.1600-0684.2006.00181.x
dc.identifier.pmid17214663
dc.identifier.urihttp://hdl.handle.net/20.500.14038/44875
dc.description.abstractBACKGROUND: A cohort of SIV-infected macaques had been used to investigate the effect of dietary supplement, immune status, SIV/AIDS disease progression and serum micronutrients levels on spontaneous acquisition of Enterocytozoon bieneusi infection in SIV-infected macaques. METHODS: Twenty-four SIV-infected macaques were randomized into 2 groups. One group received a vitamin/mineral supplementation and a second group received a placebo. Both groups were examined for E. bieneusi infection. RESULTS: SIV-infected macaques were more prone to acquire E. bieneusi with the progression of SIV/AIDS, and the increased shedding of infectious spores was directly associated with decreased CD4 lymphocyte and increased circulating SIV, in both supplemented and unsupplemented groups of animals. Dietary supplementation, body composition factors and serum micronutrients levels however had no association with the acquisition of E. bieneusi infection in these animals. CONCLUSIONS: Acquisition of E. bieneusi infection is related to SIV disease progression, CD4 counts and viral load but independent of changes in body composition and serum micronutrient levels.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=17214663&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1111/j.1600-0684.2006.00181.x
dc.subjectAnimals
dc.subjectBody Composition
dc.subjectCD4 Lymphocyte Count
dc.subjectDietary Supplements
dc.subjectDisease Progression
dc.subjectEnterocytozoon
dc.subjectMacaca mulatta
dc.subjectMicrosporidiosis
dc.subjectRisk Factors
dc.subjectSimian Acquired Immunodeficiency Syndrome
dc.subjectViral Load
dc.subjectImmunology and Infectious Disease
dc.subjectInfectious Disease
dc.subjectVeterinary Medicine
dc.titleFactors contributing to spontaneous Enterocytozoon bieneusi infection in simian immunodeficiency virus-infected macaques
dc.typeJournal Article
dc.source.journaltitleJournal of medical primatology
dc.source.volume35
dc.source.issue6
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/prevbeh_pp/297
dc.identifier.contextkey5647125
html.description.abstract<p>BACKGROUND: A cohort of SIV-infected macaques had been used to investigate the effect of dietary supplement, immune status, SIV/AIDS disease progression and serum micronutrients levels on spontaneous acquisition of Enterocytozoon bieneusi infection in SIV-infected macaques.</p> <p>METHODS: Twenty-four SIV-infected macaques were randomized into 2 groups. One group received a vitamin/mineral supplementation and a second group received a placebo. Both groups were examined for E. bieneusi infection.</p> <p>RESULTS: SIV-infected macaques were more prone to acquire E. bieneusi with the progression of SIV/AIDS, and the increased shedding of infectious spores was directly associated with decreased CD4 lymphocyte and increased circulating SIV, in both supplemented and unsupplemented groups of animals. Dietary supplementation, body composition factors and serum micronutrients levels however had no association with the acquisition of E. bieneusi infection in these animals.</p> <p>CONCLUSIONS: Acquisition of E. bieneusi infection is related to SIV disease progression, CD4 counts and viral load but independent of changes in body composition and serum micronutrient levels.</p>
dc.identifier.submissionpathprevbeh_pp/297
dc.contributor.departmentDepartment of Medicine, Division of Preventive and Behavioral Medicine
dc.source.pages352-60


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