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dc.contributor.authorKing, Jean A.
dc.contributor.authorRosal, Milagros C
dc.contributor.authorMa, Yunsheng
dc.contributor.authorReed, George W.
dc.contributor.authorKelly, Terri-Ann
dc.contributor.authorStanek, Edward J. III
dc.contributor.authorOckene, Ira S.
dc.date2022-08-11T08:10:21.000
dc.date.accessioned2022-08-23T17:05:42Z
dc.date.available2022-08-23T17:05:42Z
dc.date.issued2001-01-09
dc.date.submitted2008-01-15
dc.identifier.citationBehav Med. 2000 Summer;26(2):67-73.
dc.identifier.issn0896-4289 (Print)
dc.identifier.pmid11147291
dc.identifier.urihttp://hdl.handle.net/20.500.14038/44915
dc.description.abstractAssessments of cortisol levels in saliva have been widely used by both researchers and clinicians as an index of adrenal functioning. Quarterly measurements of morning and evening cortisol levels were determined in a longitudinal study of 147 participants (72 women and 75 men) followed for 1 year each. The analysis of salivary cortisol revealed no significant gender or age differences in the sample. There was a sequence effect in quarterly cortisol values with a progressive decrease in serial measurements, especially notable in the morning values; as well as a seasonal variation in cortisol levels with significantly higher levels found in winter and fall, compared with spring and summer. The findings in this study suggest that repeated saliva sampling and seasonal variation in cortisol levels may independently affect adrenal response and, therefore, need to be accounted for in longitudinal studies.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11147291&dopt=Abstract ">Link to article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1080/08964280009595753
dc.subjectAdult
dc.subjectAged
dc.subjectArousal
dc.subjectCholesterol
dc.subjectCircadian Rhythm
dc.subjectFemale
dc.subjectHumans
dc.subjectHydrocortisone
dc.subjectHypothalamo-Hypophyseal System
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPituitary-Adrenal System
dc.subjectReference Values
dc.subjectSaliva
dc.subject*Seasons
dc.subjectBehavioral Disciplines and Activities
dc.subjectBehavior and Behavior Mechanisms
dc.subjectCommunity Health and Preventive Medicine
dc.subjectPreventive Medicine
dc.titleSequence and seasonal effects of salivary cortisol
dc.typeJournal Article
dc.source.journaltitleBehavioral medicine (Washington, D.C.)
dc.source.volume26
dc.source.issue2
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/prevbeh_pp/35
dc.identifier.contextkey413371
html.description.abstract<p>Assessments of cortisol levels in saliva have been widely used by both researchers and clinicians as an index of adrenal functioning. Quarterly measurements of morning and evening cortisol levels were determined in a longitudinal study of 147 participants (72 women and 75 men) followed for 1 year each. The analysis of salivary cortisol revealed no significant gender or age differences in the sample. There was a sequence effect in quarterly cortisol values with a progressive decrease in serial measurements, especially notable in the morning values; as well as a seasonal variation in cortisol levels with significantly higher levels found in winter and fall, compared with spring and summer. The findings in this study suggest that repeated saliva sampling and seasonal variation in cortisol levels may independently affect adrenal response and, therefore, need to be accounted for in longitudinal studies.</p>
dc.identifier.submissionpathprevbeh_pp/35
dc.contributor.departmentDepartment of Medicine, Division of Cardiovascular Medicine
dc.contributor.departmentDepartment of Psychiatry
dc.contributor.departmentDepartment of Medicine, Division of Preventive and Behavorial Medicine
dc.source.pages67-73


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