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dc.contributor.authorSpring, Bonnie J.
dc.contributor.authorSchneider, Kristin L.
dc.contributor.authorSmith, Malaina
dc.contributor.authorKendzor, Darla
dc.contributor.authorAppelhans, Bradley M.
dc.contributor.authorHedeker, Donald
dc.contributor.authorPagoto, Sherry L.
dc.date2022-08-11T08:10:22.000
dc.date.accessioned2022-08-23T17:05:59Z
dc.date.available2022-08-23T17:05:59Z
dc.date.issued2008-02-15
dc.date.submitted2010-07-26
dc.identifier.citationPsychopharmacology (Berl). 2008 May;197(4):637-47. Epub 2008 Feb 14. <a href="http://dx.doi.org/10.1007/s00213-008-1085-z">Link to article on publisher's site</a>
dc.identifier.issn0033-3158 (Linking)
dc.identifier.doi10.1007/s00213-008-1085-z
dc.identifier.pmid18273603
dc.identifier.urihttp://hdl.handle.net/20.500.14038/44983
dc.description.abstractRATIONALE: The long-rejected construct of food addiction is undergoing re-examination. OBJECTIVES: To evaluate whether a novel carbohydrate food shows abuse potential for rigorously defined carbohydrate cravers, as evidenced by selective self-administration and mood enhancement during double-blind discrimination testing. MATERIALS AND METHODS: Discrete trials choice testing was performed with 61 overweight (BMI m = 27.64, SD = 2.59) women (ages 18-45; 19.70% African American) whose diet records showed >4 weekly afternoon/evening emotional-eating episodes confined to snacks with carbohydrate to protein ratio of >6:1. After being induced into a sad mood, participants were exposed, double-blind and in counterbalanced order, to taste-matched carbohydrate and protein beverages. They were asked to choose and self-administer the drink that made them feel better. RESULTS: Women overwhelmingly chose the carbohydrate beverage, even though blinded. Mixed-effects regression modeling, controlling for beverage order, revealed greater liking and greater reduction in dysphoria after administration of the carbohydrate beverage compared to the protein beverage but no differential effect on vigor. CONCLUSION: For women who crave them, carbohydrates appear to display abuse potential, plausibly contributing to overconsumption and overweight.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=18273603&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1007/s00213-008-1085-z
dc.subjectAdolescent
dc.subjectAdult
dc.subject*Affect
dc.subjectBehavior, Addictive
dc.subjectChoice Behavior
dc.subjectDietary Carbohydrates
dc.subjectDietary Proteins
dc.subjectDouble-Blind Method
dc.subjectEating Disorders
dc.subjectFemale
dc.subjectFood Preferences
dc.subjectHumans
dc.subjectMiddle Aged
dc.subject*Motivation
dc.subjectOverweight
dc.subjectSelf Administration
dc.subjectTaste
dc.subjectBehavioral Disciplines and Activities
dc.subjectBehavior and Behavior Mechanisms
dc.subjectCommunity Health and Preventive Medicine
dc.subjectPreventive Medicine
dc.titleAbuse potential of carbohydrates for overweight carbohydrate cravers
dc.typeJournal Article
dc.source.journaltitlePsychopharmacology
dc.source.volume197
dc.source.issue4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/prevbeh_pp/93
dc.identifier.contextkey1409520
html.description.abstract<p>RATIONALE: The long-rejected construct of food addiction is undergoing re-examination.</p> <p>OBJECTIVES: To evaluate whether a novel carbohydrate food shows abuse potential for rigorously defined carbohydrate cravers, as evidenced by selective self-administration and mood enhancement during double-blind discrimination testing.</p> <p>MATERIALS AND METHODS: Discrete trials choice testing was performed with 61 overweight (BMI m = 27.64, SD = 2.59) women (ages 18-45; 19.70% African American) whose diet records showed >4 weekly afternoon/evening emotional-eating episodes confined to snacks with carbohydrate to protein ratio of >6:1. After being induced into a sad mood, participants were exposed, double-blind and in counterbalanced order, to taste-matched carbohydrate and protein beverages. They were asked to choose and self-administer the drink that made them feel better.</p> <p>RESULTS: Women overwhelmingly chose the carbohydrate beverage, even though blinded. Mixed-effects regression modeling, controlling for beverage order, revealed greater liking and greater reduction in dysphoria after administration of the carbohydrate beverage compared to the protein beverage but no differential effect on vigor.</p> <p>CONCLUSION: For women who crave them, carbohydrates appear to display abuse potential, plausibly contributing to overconsumption and overweight.</p>
dc.identifier.submissionpathprevbeh_pp/93
dc.contributor.departmentDepartment of Medicine, Division of Preventive and Behavioral Medicine
dc.source.pages637-47


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