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    Early sexual abuse and low cortisol

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    Authors
    King, Jean A.
    Mandansky, Deborah
    King, Susie
    Fletcher, Kenneth E.
    Brewer, Judith
    UMass Chan Affiliations
    Department of Psychiatry
    Document Type
    Journal Article
    Publication Date
    2001-03-10
    Keywords
    Child
    Child Abuse, Sexual
    Child, Preschool
    Female
    Humans
    Hydrocortisone
    Hypothalamo-Hypophyseal System
    Stress Disorders, Post-Traumatic
    Mental and Social Health
    Psychiatric and Mental Health
    Psychiatry
    Psychiatry and Psychology
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    Link to Full Text
    http://dx.doi.org/10.1046/j.1440-1819.2001.00787.x
    Abstract
    Post-traumatic stress disorder (PTSD) is a mental health disorder precipitated by a stressful event that produces fear or terror in the individual. Post-traumatic stress disorder studies, particularly in early sexual abuse, have been associated with neuroendocrine dysfunction, most notably the hypothalamic-pituitary-adrenal (HPA) axis. Since the literature on PTSD and neuroendocrine factors in young subjects has been sparse, the present studies were designed to look at the basal functioning of the HPA axis in response to early sexual abuse in girls aged 5 to 7 years. Morning salivary samples were collected for cortisol determination from subjects and controls who were scheduled for a physical exam by their pediatrician. The present study shows that subjects who had been abused within the last couple of months had significantly lower cortisol in comparison to control subjects (age, social economic status and race matched). The data suggest that children may have an impaired HPA axis after early trauma.
    Source
    Psychiatry Clin Neurosci. 2001 Feb;55(1):71-4.
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/45019
    PubMed ID
    11235861
    Related Resources
    Link to Article in PubMed
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    UMass Chan Faculty and Researcher Publications

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