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    Choroid plexus blood flow: evidence for dopaminergic influence

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    Authors
    Townsend, John B.
    Ziedonis, Douglas M.
    Bryan, Robert M.
    Brennan, Robert W.
    Page, Robert B.
    UMass Chan Affiliations
    Department of Psychiatry
    Document Type
    Journal Article
    Publication Date
    1984-01-02
    Keywords
    Animals
    Cerebral Cortex
    Choroid Plexus
    Dopamine
    Female
    Haloperidol
    Propranolol
    Regional Blood Flow
    Renal Circulation
    Sheep
    Psychiatry
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    Link to Full Text
    http://dx.doi.org/10.1016/0006-8993(84)90748-0
    Abstract
    Choroid plexus blood flow was measured in adult female sheep using the radioactive microsphere technique. The response of choroid plexus, renal and cortical blood flow to the infusion of dopamine (11 sheep), haloperidol (7 sheep) and propranolol (6 sheep) were compared. Choroid plexus and renal blood flow significantly increased after dopamine infusion (55% and 49% respectively). Choroid plexus and renal blood flow decreased significantly following haloperidol infusion (-24% and 29% respectively). Cortical blood flow did not significantly change. Propranolol infusion did not significantly change blood flow in these regions. These observations suggest that dopaminergic mechanisms play a role in the regulation of choroid plexus as well as renal blood flow.
    Source
    Brain Res. 1984 Jan 2;290(1):165-9.
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/45625
    PubMed ID
    6692134
    Related Resources
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