Mania in children with pervasive developmental disorder revisited
Name:
Publisher version
View Source
Access full-text PDFOpen Access
View Source
Check access options
Check access options
Authors
Wozniak, JanetBiederman, Joseph
Faraone, Stephen V.
Frazier, Jean A.
Kim, Jane
Millstein, Rachael
Gershon, Jonathan
Thornell, Ayanna
Cha, Kristine
Snyder, James B.
UMass Chan Affiliations
Department of PsychiatryDocument Type
Journal ArticlePublication Date
1997-12-12Keywords
Bipolar DisorderChild
Child Development Disorders, Pervasive
Comorbidity
Female
Humans
Male
Prevalence
Psychiatry
Metadata
Show full item recordAbstract
OBJECTIVE: Although a small literature of case reports suggests that mania co-occurs with pervasive developmental disorder (PDD), little is known about this overlap. The authors systematically investigated the overlap between mania and PDD in a consecutive sample of referred youths, examining its prevalence and correlates. It was hypothesized that children with PDD plus manic features have both disorders. METHOD: Subjects were consecutively referred children meeting diagnostic criteria on structured interview for PDD without mania (n = 52), the comorbid condition PDD + mania (n = 14), and mania without PDD (n = 114). All subjects were evaluated using a comprehensive diagnostic battery that included assessment of psychopathology (structured diagnostic interview and Child Behavior Checklist), cognition, and functioning. RESULTS: Of the 727 referred children, 52 met criteria for PDD, 114 met criteria for mania, and 14 met criteria for both. The 14 children with both PDD + mania represented 21% of the PDD subjects and 11% of all manic subjects. Clinical characteristics of PDD were similar in PDD subjects with and without mania, and manic features were similar in manic children with and without PDD. CONCLUSIONS: Children with PDD and mania may suffer from two disorders. Comorbid mania among patients with PDD may be more common than previously thought. Identification of the comorbid condition may have important therapeutic and scientific implications.Source
J Am Acad Child Adolesc Psychiatry. 1997 Nov;36(11):1552-9; discussion 1559-60. Link to article on publisher's siteDOI
10.1016/S0890-8567(09)66564-3Permanent Link to this Item
http://hdl.handle.net/20.500.14038/45847PubMed ID
9394940Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/S0890-8567(09)66564-3