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    Mania in children with pervasive developmental disorder revisited

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    Authors
    Wozniak, Janet
    Biederman, Joseph
    Faraone, Stephen V.
    Frazier, Jean A.
    Kim, Jane
    Millstein, Rachael
    Gershon, Jonathan
    Thornell, Ayanna
    Cha, Kristine
    Snyder, James B.
    UMass Chan Affiliations
    Department of Psychiatry
    Document Type
    Journal Article
    Publication Date
    1997-12-12
    Keywords
    Bipolar Disorder
    Child
    Child Development Disorders, Pervasive
    Comorbidity
    Female
    Humans
    Male
    Prevalence
    Psychiatry
    
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    Link to Full Text
    http://dx.doi.org/10.1016/S0890-8567(09)66564-3
    Abstract
    OBJECTIVE: Although a small literature of case reports suggests that mania co-occurs with pervasive developmental disorder (PDD), little is known about this overlap. The authors systematically investigated the overlap between mania and PDD in a consecutive sample of referred youths, examining its prevalence and correlates. It was hypothesized that children with PDD plus manic features have both disorders. METHOD: Subjects were consecutively referred children meeting diagnostic criteria on structured interview for PDD without mania (n = 52), the comorbid condition PDD + mania (n = 14), and mania without PDD (n = 114). All subjects were evaluated using a comprehensive diagnostic battery that included assessment of psychopathology (structured diagnostic interview and Child Behavior Checklist), cognition, and functioning. RESULTS: Of the 727 referred children, 52 met criteria for PDD, 114 met criteria for mania, and 14 met criteria for both. The 14 children with both PDD + mania represented 21% of the PDD subjects and 11% of all manic subjects. Clinical characteristics of PDD were similar in PDD subjects with and without mania, and manic features were similar in manic children with and without PDD. CONCLUSIONS: Children with PDD and mania may suffer from two disorders. Comorbid mania among patients with PDD may be more common than previously thought. Identification of the comorbid condition may have important therapeutic and scientific implications.
    Source
    J Am Acad Child Adolesc Psychiatry. 1997 Nov;36(11):1552-9; discussion 1559-60. Link to article on publisher's site
    DOI
    10.1016/S0890-8567(09)66564-3
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/45847
    PubMed ID
    9394940
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1016/S0890-8567(09)66564-3
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