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Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series

dc.contributor.authorDoyle, Robert L.
dc.contributor.authorFrazier, Jean A.
dc.contributor.authorSpencer, Thomas J.
dc.contributor.authorGeller, Daniel A.
dc.contributor.authorBiederman, Joseph
dc.contributor.authorWilens, Timothy E.
dc.date2022-08-11T08:10:27.000
dc.date.accessioned2022-08-23T17:09:40Z
dc.date.available2022-08-23T17:09:40Z
dc.date.issued2006-02-17
dc.date.submitted2011-02-10
dc.identifier.citationJ Atten Disord. 2006 Feb;9(3):543-9. <a href="http://dx.doi.org/10.1177/1087054705284091">Link to article on publisher's site</a>
dc.identifier.issn1087-0547 (Linking)
dc.identifier.doi10.1177/1087054705284091
dc.identifier.pmid16481671
dc.identifier.urihttp://hdl.handle.net/20.500.14038/45874
dc.description.abstractBACKGROUND: Recent studies reported ADHD-like symptoms and cognitive deficits in pervasive developmental disorder (PDD). Because work in dementia documents improvement in executive function deficits with the acetylcholinesterase inhibitor donepezil, the authors reason that similar benefits could be obtained in PDD. METHOD: The authors describe eight cases of PDD youth ages 10 to 17 treated with donepezil targeting ADHD-like symptoms associated with PDD. RESULTS: Most participants improve ADHD-like symptomatology. In addition, improvement in communication and socialization is noted. CONCLUSION: Donepezil may have a role in treating ADHD-like symptoms in children with PDD.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=16481671&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1177/1087054705284091
dc.subjectAdolescent
dc.subjectAttention Deficit Disorder with Hyperactivity
dc.subjectChild
dc.subjectChild Development Disorders, Pervasive
dc.subjectCholinesterase Inhibitors
dc.subjectCommunication
dc.subjectDrug Administration Schedule
dc.subjectFemale
dc.subjectHumans
dc.subjectIndans
dc.subjectMale
dc.subjectPiperidines
dc.subjectSocial Behavior
dc.subjectPsychiatry
dc.titleDonepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series
dc.typeJournal Article
dc.source.journaltitleJournal of attention disorders
dc.source.volume9
dc.source.issue3
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/psych_pp/402
dc.identifier.contextkey1775340
html.description.abstract<p>BACKGROUND: Recent studies reported ADHD-like symptoms and cognitive deficits in pervasive developmental disorder (PDD). Because work in dementia documents improvement in executive function deficits with the acetylcholinesterase inhibitor donepezil, the authors reason that similar benefits could be obtained in PDD.</p> <p>METHOD: The authors describe eight cases of PDD youth ages 10 to 17 treated with donepezil targeting ADHD-like symptoms associated with PDD.</p> <p>RESULTS: Most participants improve ADHD-like symptomatology. In addition, improvement in communication and socialization is noted.</p> <p>CONCLUSION: Donepezil may have a role in treating ADHD-like symptoms in children with PDD.</p>
dc.identifier.submissionpathpsych_pp/402
dc.contributor.departmentDepartment of Psychiatry
dc.source.pages543-9


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