A delusion assessment scale for psychotic major depression: Reliability, validity, and utility
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Authors
Meyers, Barnett S.English, Judith
Gabriele, Michelle
Peasley-Miklus, Catherine
Heo, Moonseong
Flint, Alastair J.
Mulsant, Benoit H.
Rothschild, Anthony J.
UMass Chan Affiliations
Department of PsychiatryDocument Type
Journal ArticlePublication Date
2006-10-19Keywords
AdultAffect
Antipsychotic Agents
Benzodiazepines
Delusions
Depressive Disorder, Major
Double-Blind Method
Female
Humans
Male
Observer Variation
Principal Component Analysis
Psychiatric Status Rating Scales
Reproducibility of Results
Serotonin Uptake Inhibitors
Sertraline
Psychiatry
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BACKGROUND: Although delusions are the hallmark of major depression with psychotic features, a scale to measure the intensity of beliefs across multiple delusional domains in this condition has been unavailable. The development and assessment of the Delusional Assessment Scale (DAS) are described. METHODS: Scale items were selected initially based on previous studies of delusional ideation in schizophrenia. A three-point item to assess mood congruence was added. A 15-item scale was assessed in 92 subjects participating in the four-site collaborative study of the pharmacotherapy of major depression with psychotic features. Maximum likelihood method was used to determine scale factors. The internal consistency of these factors was determined. Comparisons between scale scores and ratings from the Brief Psychiatric Rating Scale (BPRS) (Overall and Gorham 1962) were used to assess convergent and discriminant validity. RESULTS: The data were fit by a five-factors model (impact, conviction, disorganization, bizarreness, and extension). Inter-rater reliability of the five factors ranged from .77 for conviction and .74 for impact to .37 for disorganization. Internal consistency for each of the five factors was > or =.72. Scores on specific domains were significantly correlated with the BPRS unusual thought content item and positive symptom subscale scores. CONCLUSIONS: The DAS is a reliable measure of 5 delusional domains.Source
Biol Psychiatry. 2006 Dec 15;60(12):1336-42. Epub 2006 Oct 13. Link to article on publisher's siteDOI
10.1016/j.biopsych.2006.05.033Permanent Link to this Item
http://hdl.handle.net/20.500.14038/46081PubMed ID
17046724Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/j.biopsych.2006.05.033