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    A delusion assessment scale for psychotic major depression: Reliability, validity, and utility

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    Authors
    Meyers, Barnett S.
    English, Judith
    Gabriele, Michelle
    Peasley-Miklus, Catherine
    Heo, Moonseong
    Flint, Alastair J.
    Mulsant, Benoit H.
    Rothschild, Anthony J.
    UMass Chan Affiliations
    Department of Psychiatry
    Document Type
    Journal Article
    Publication Date
    2006-10-19
    Keywords
    Adult
    Affect
    Antipsychotic Agents
    Benzodiazepines
    Delusions
    Depressive Disorder, Major
    Double-Blind Method
    Female
    Humans
    Male
    Observer Variation
    Principal Component Analysis
    Psychiatric Status Rating Scales
    Reproducibility of Results
    Serotonin Uptake Inhibitors
    Sertraline
    Psychiatry
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    Link to Full Text
    http://dx.doi.org/10.1016/j.biopsych.2006.05.033
    Abstract
    BACKGROUND: Although delusions are the hallmark of major depression with psychotic features, a scale to measure the intensity of beliefs across multiple delusional domains in this condition has been unavailable. The development and assessment of the Delusional Assessment Scale (DAS) are described. METHODS: Scale items were selected initially based on previous studies of delusional ideation in schizophrenia. A three-point item to assess mood congruence was added. A 15-item scale was assessed in 92 subjects participating in the four-site collaborative study of the pharmacotherapy of major depression with psychotic features. Maximum likelihood method was used to determine scale factors. The internal consistency of these factors was determined. Comparisons between scale scores and ratings from the Brief Psychiatric Rating Scale (BPRS) (Overall and Gorham 1962) were used to assess convergent and discriminant validity. RESULTS: The data were fit by a five-factors model (impact, conviction, disorganization, bizarreness, and extension). Inter-rater reliability of the five factors ranged from .77 for conviction and .74 for impact to .37 for disorganization. Internal consistency for each of the five factors was > or =.72. Scores on specific domains were significantly correlated with the BPRS unusual thought content item and positive symptom subscale scores. CONCLUSIONS: The DAS is a reliable measure of 5 delusional domains.
    Source
    Biol Psychiatry. 2006 Dec 15;60(12):1336-42. Epub 2006 Oct 13. Link to article on publisher's site
    DOI
    10.1016/j.biopsych.2006.05.033
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/46081
    PubMed ID
    17046724
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.biopsych.2006.05.033
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