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Peripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures

dc.contributor.authorBabb, Jessica A.
dc.contributor.authorDeligiannidis, Kristina M.
dc.contributor.authorMurgatroyd, Christopher A.
dc.contributor.authorNephew, Benjamin C.
dc.date2022-08-11T08:10:29.000
dc.date.accessioned2022-08-23T17:10:51Z
dc.date.available2022-08-23T17:10:51Z
dc.date.issued2014-04-04
dc.date.submitted2014-09-16
dc.identifier.citationBehav Brain Res. 2014 Apr 4. doi: 10.1016/j.bbr.2014.03.039. <a href="http://dx.doi.org/10.1016/j.bbr.2014.03.039">Link to article on publisher's site</a>
dc.identifier.issn0166-4328 (Linking)
dc.identifier.doi10.1016/j.bbr.2014.03.039
dc.identifier.pmid24709228
dc.identifier.urihttp://hdl.handle.net/20.500.14038/46139
dc.description.abstractExposure to high levels of early life stress has been identified as a potent risk factor for neurodevelopmental delays in infants, behavioral problems and autism in children, but also for several psychiatric illnesses in adulthood, such as depression, anxiety, autism, and posttraumatic stress disorder. Despite having robust adverse effects on both mother and infant, the pathophysiology of peripartum depression and anxiety are poorly understood. The objective of this review is to highlight the advantages of using an integrated approach addressing several behavioral domains in both animal and clinical studies of peripartum depression and anxiety. It is postulated that a greater focus on integrated cross domain studies will lead to advances in treatments and preventative measures for several disorders associated with peripartum depression and anxiety.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=24709228&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx/doi.org/10.1016/j.bbr.2014.03.039
dc.subjectMaternal and Child Health
dc.subjectMental and Social Health
dc.subjectNeuroscience and Neurobiology
dc.subjectPsychiatry
dc.subjectPsychiatry and Psychology
dc.subjectWomen's Health
dc.titlePeripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures
dc.typeJournal Article
dc.source.journaltitleBehavioural brain research
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/psych_pp/675
dc.identifier.contextkey6123888
html.description.abstract<p>Exposure to high levels of early life stress has been identified as a potent risk factor for neurodevelopmental delays in infants, behavioral problems and autism in children, but also for several psychiatric illnesses in adulthood, such as depression, anxiety, autism, and posttraumatic stress disorder. Despite having robust adverse effects on both mother and infant, the pathophysiology of peripartum depression and anxiety are poorly understood. The objective of this review is to highlight the advantages of using an integrated approach addressing several behavioral domains in both animal and clinical studies of peripartum depression and anxiety. It is postulated that a greater focus on integrated cross domain studies will lead to advances in treatments and preventative measures for several disorders associated with peripartum depression and anxiety.</p>
dc.identifier.submissionpathpsych_pp/675
dc.contributor.departmentDepartment of Psychiatry


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