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Authors
Krishnaswami, AshokSteinman, Michael A.
Goyal, Parag
Zullo, Andrew R.
Anderson, Timothy S.
Birtcher, Kim K.
Goodlin, Sarah J.
Maurer, Mathew S.
Alexander, Karen P.
Rich, Michael W.
Tjia, Jennifer
UMass Chan Affiliations
Department of Population and Quantitative Health SciencesDocument Type
Journal ArticlePublication Date
2019-05-28Keywords
deprescribinggeriatrics
medications
multimorbidity
multiple chronic conditions
older adults
polypharmacy
Cardiology
Cardiovascular Diseases
Epidemiology
Geriatrics
Health Services Administration
Health Services Research
Pharmaceutical Preparations
Therapeutics
Metadata
Show full item recordAbstract
Deprescribing, an integral component of a continuum of good prescribing practices, is the process of medication withdrawal or dose reduction to correct or prevent medication-related complications, improve outcomes, and reduce costs. Deprescribing is particularly applicable to the commonly encountered multimorbid older adult with cardiovascular disease and concomitant geriatric conditions such as polypharmacy, frailty, and cognitive dysfunction-a combination rarely addressed in current clinical practice guidelines. Triggers to deprescribe include present or expected adverse drug reactions, unnecessary polypharmacy, and the need to align medications with goals of care when life expectancy is reduced. Using a framework to deprescribe, this review addresses the rationale, evidence, and strategies for deprescribing cardiovascular and some noncardiovascular medications.Source
J Am Coll Cardiol. 2019 May 28;73(20):2584-2595. doi: 10.1016/j.jacc.2019.03.467. Link to article on publisher's site
DOI
10.1016/j.jacc.2019.03.467Permanent Link to this Item
http://hdl.handle.net/20.500.14038/46795PubMed ID
31118153Related Resources
ae974a485f413a2113503eed53cd6c53
10.1016/j.jacc.2019.03.467