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dc.contributor.authorOates, Gabriela R.
dc.contributor.authorJuarez, Lucia D.
dc.contributor.authorHansen, Barbara
dc.contributor.authorKiefe, Catarina I.
dc.contributor.authorShikany, James M.
dc.date2022-08-11T08:10:36.000
dc.date.accessioned2022-08-23T17:14:00Z
dc.date.available2022-08-23T17:14:00Z
dc.date.issued2020-03-01
dc.date.submitted2020-03-23
dc.identifier.citation<p>Oates GR, Juarez LD, Hansen B, Kiefe CI, Shikany JM. Social Risk Factors for Medication Nonadherence: Findings from the CARDIA Study. Am J Health Behav. 2020 Mar 1;44(2):232-243. doi: 10.5993/AJHB.44.2.10. PMID: 32019655. <a href="https://doi.org/10.5993/AJHB.44.2.10">Link to article on publisher's site</a></p>
dc.identifier.issn1087-3244 (Linking)
dc.identifier.doi10.5993/AJHB.44.2.10
dc.identifier.pmid32019655
dc.identifier.urihttp://hdl.handle.net/20.500.14038/46860
dc.description.abstractObjectives: Nonadherence to medications has been documented, but the combined effect of social risk factors on medication nonadherence has not been investigated. Methods: We conducted a cross-sectional analysis of data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based prospective cohort. The sample (N = 1506) included subjects who at Year 20 (2005-06) were taking prescription medications and completed a 4-item Medication Adherence Scale. Social risk factors were education of high school or less, annual household income < $25,000, high financial strain, high chronic stress, low social support, and high social strain. Results: In a fully adjusted logistic regression model, income < $25,000 (OR = 2.37 [95% CI 1.12-4.98], p < .05) and high chronic stress (OR = 2.07 [95% CI 1.09-3.94], p < .05) were significantly associated with medication nonadherence. Individuals with > /=3 social risk factors had > 3 times higher odds of nonadherence than counterparts with no social risk factors (OR = 3.26 [95% CI 1.72-6.19], p < .001). Conclusion: Low income and chronic stress are associated with medication nonadherence, and the odds of nonadherence increase with the accumulation of social risk factors. Findings may be used to develop risk prediction tools to identify individuals who can benefit from adherence-promoting interventions.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=32019655&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttps://doi.org/10.5993/AJHB.44.2.10
dc.subjectmedication adherence
dc.subjectsocial factors
dc.subjectincome
dc.subjectchronic stress
dc.subjectBehavioral Medicine
dc.subjectEpidemiology
dc.subjectHealth Psychology
dc.subjectHealth Services Research
dc.subjectPsychiatry and Psychology
dc.titleSocial Risk Factors for Medication Nonadherence: Findings from the CARDIA Study
dc.typeJournal Article
dc.source.journaltitleAmerican journal of health behavior
dc.source.volume44
dc.source.issue2
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/qhs_pp/1330
dc.identifier.contextkey16955911
html.description.abstract<p>Objectives: Nonadherence to medications has been documented, but the combined effect of social risk factors on medication nonadherence has not been investigated.</p> <p>Methods: We conducted a cross-sectional analysis of data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based prospective cohort. The sample (N = 1506) included subjects who at Year 20 (2005-06) were taking prescription medications and completed a 4-item Medication Adherence Scale. Social risk factors were education of high school or less, annual household income < $25,000, high financial strain, high chronic stress, low social support, and high social strain.</p> <p>Results: In a fully adjusted logistic regression model, income < $25,000 (OR = 2.37 [95% CI 1.12-4.98], p < .05) and high chronic stress (OR = 2.07 [95% CI 1.09-3.94], p < .05) were significantly associated with medication nonadherence. Individuals with > /=3 social risk factors had > 3 times higher odds of nonadherence than counterparts with no social risk factors (OR = 3.26 [95% CI 1.72-6.19], p < .001).</p> <p>Conclusion: Low income and chronic stress are associated with medication nonadherence, and the odds of nonadherence increase with the accumulation of social risk factors. Findings may be used to develop risk prediction tools to identify individuals who can benefit from adherence-promoting interventions.</p>
dc.identifier.submissionpathqhs_pp/1330
dc.contributor.departmentDepartment of Population and Quantitative Health Sciences
dc.source.pages232-243


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