UMass Chan AffiliationsDepartment of Population and Quantitative Health Sciences
Document TypeConference Paper
Keywordsadverse drug reactions
neural multi-task learning system
Artificial Intelligence and Robotics
Chemicals and Drugs
Health Information Technology
Health Services Research
MetadataShow full item record
AbstractA reliable and searchable knowledge database of adverse drug reactions (ADRs) is highly important and valuable for improving patient safety at the point of care. In this paper, we proposed a neural multi-task learning system, NeuroADR, to extract ADRs as well as relevant modifiers from free-text drug labels. Specifically, the NeuroADR system exploited a hierarchical multi-task learning (HMTL) framework to perform named entity recognition (NER) and relation extraction (RE) jointly, where interactions among the learned deep encoder representations from different subtasks are explored. Different from the conventional HMTL approach, NeuroADR adopted a novel task decomposition strategy to generate auxiliary subtasks for more inter-task interactions and integrated a new label encoding schema for better handling discontinuous entities. Experimental results demonstrate the effectiveness of the proposed system.
Liu F, Zheng X, Yu H, Tjia J. Neural Multi-Task Learning for Adverse Drug Reaction Extraction. AMIA Annu Symp Proc. 2021 Jan 25;2020:756-762. PMID: 33936450; PMCID: PMC8075418.