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dc.contributor.authorHoaglin, David C.
dc.date2022-08-11T08:10:37.000
dc.date.accessioned2022-08-23T17:14:26Z
dc.date.available2022-08-23T17:14:26Z
dc.date.issued2021-06-10
dc.date.submitted2021-10-21
dc.identifier.citation<p>Hoaglin DC. Letter to the Editor on detecting and dealing with heterogeneity in meta-analyses by Cordero and Dans. J Clin Epidemiol. 2021 Jun 10:S0895-4356(21)00181-5. doi: 10.1016/j.jclinepi.2021.06.003. Epub ahead of print. PMID: 34118366. <a href="https://doi.org/10.1016/j.jclinepi.2021.06.003">Link to article on publisher's site</a></p>
dc.identifier.issn0895-4356 (Linking)
dc.identifier.doi10.1016/j.jclinepi.2021.06.003
dc.identifier.pmid34118366
dc.identifier.urihttp://hdl.handle.net/20.500.14038/46954
dc.description.abstractCordero and Dans give valuable advice on various aspects of detecting and dealing with heterogeneity in meta-analyses. For assessing statistical heterogeneity, they start with a forest plot of the study-level effect estimates and complement it with 2 related numerical measures, Q and I2. Other recommended approaches in the literature include the between-study standard deviation and a prediction interval for the effect in a new study. All these approaches have shortcomings, which investigation of heterogeneity should take into account. Surprisingly, the limitations of Q and I2, the 2 most popular, are not yet widely understood.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=34118366&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttps://doi.org/10.1016/j.jclinepi.2021.06.003
dc.subjectHeterogeneity
dc.subjectQ statistic
dc.subjectI2
dc.subjectBiostatistics
dc.subjectClinical Epidemiology
dc.subjectEpidemiology
dc.subjectHealth Services Research
dc.titleLetter to the Editor on detecting and dealing with heterogeneity in meta-analyses by Cordero and Dans
dc.typeLetter to the Editor
dc.source.journaltitleJournal of clinical epidemiology
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/qhs_pp/1433
dc.identifier.contextkey25551198
html.description.abstract<p>Cordero and Dans give valuable advice on various aspects of detecting and dealing with heterogeneity in meta-analyses. For assessing statistical heterogeneity, they start with a forest plot of the study-level effect estimates and complement it with 2 related numerical measures, <em>Q</em> and <em>I</em><sup>2</sup>. Other recommended approaches in the literature include the between-study standard deviation and a prediction interval for the effect in a new study. All these approaches have shortcomings, which investigation of heterogeneity should take into account. Surprisingly, the limitations of <em>Q</em> and <em>I</em><sup>2</sup>, the 2 most popular, are not yet widely understood.</p>
dc.identifier.submissionpathqhs_pp/1433
dc.contributor.departmentDivision of Biostatistics and Health Services Research, Department of Population and Quantitative Health Sciences


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