Frequencies of sickle cell trait and glucose-6-phosphate dehydrogenase deficiency differ in highland and nearby lowland malaria-endemic areas of Kenya
AuthorsMoormann, Ann M.
Embury, Paula E.
Sumba, Peter Odada
Ouma, J. H.
Kazura, James W.
John, Chandy C.
Document TypeJournal Article
Glucosephosphate Dehydrogenase Deficiency
Sickle Cell Trait
Health Services Research
Immunology and Infectious Disease
MetadataShow full item record
AbstractSickle cell genotype prevalence was 26% in a malaria-holoendemic lowland area compared with 3% in a highland area of Kenya. The prevalence of glucose-6-phosphate dehydrogenase deficiency was 7% and 1% in holoendemic lowland and highland areas, respectively. Lack of protective polymorphisms may contribute to morbidity and mortality during outbreaks of malaria in the highlands.
SourceTrans R Soc Trop Med Hyg. 2003 Sep-Oct;97(5):513-4. Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/47241
Related ResourcesLink to Article in PubMed