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    Health-related quality of life associated with chronic conditions in eight countries: results from the International Quality of Life Assessment (IQOLA) Project

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    Authors
    Alonso, Jordi
    Ferrer, Montserrat
    Gandek, Barbara
    Ware, John E. Jr.
    Aaronson, Neil K.
    Mosconi, Paola
    Rasmussen, Niels K.
    Bullinger, Monika
    Fukuhara, Shunichi
    Kaasa, Stein
    Leplege, Alain
    Show allShow less
    UMass Chan Affiliations
    Department of Quantitative Health Sciences
    Document Type
    Journal Article
    Publication Date
    2004-04-17
    Keywords
    Adult
    Chronic Disease
    Comorbidity
    Cross-Cultural Comparison
    Cross-Sectional Studies
    Europe
    Female
    Humans
    Japan
    Linear Models
    Male
    Middle Aged
    Prevalence
    *Quality of Life
    *Sickness Impact Profile
    United States
    Biostatistics
    Epidemiology
    Health Services Research
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    Metadata
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    Link to Full Text
    http://dx.doi.org/10.1023/B:QURE.0000018472.46236.05
    Abstract
    CONTEXT: Few studies and no international comparisons have examined the impact of multiple chronic conditions on populations using a comprehensive health-related quality of life (HRQL) questionnaire. OBJECTIVE: The impact of common chronic conditions on HRQL among the general populations of eight countries was assessed. DESIGN: Cross-sectional mail and interview surveys were conducted. PARTICIPANTS AND SETTING: Sample representatives of the adult general population of eight countries (Denmark, France, Germany, Italy, Japan, The Netherlands, Norway and the United States) were evaluated. Sample sizes ranged from 2031 to 4084. MAIN OUTCOME MEASURES: Self-reported prevalence of chronic conditions (including allergies, arthritis, congestive heart failure, chronic lung disease, hypertension, diabetes, and ischemic heart disease), sociodemographic data and the SF-36 Health Survey were obtained. The SF-36 scale and summary scores were estimated for individuals with and without selected chronic conditions and compared across countries using multivariate linear regression analyses. Adjustments were made for age, gender, marital status, education and the mode of SF-36 administration. RESULTS: More than half (55.1%) of the pooled sample reported at least one chronic condition, and 30.2% had more than one. Hypertension, allergies and arthritis were the most frequently reported conditions. The effect of ischemic heart disease on many of the physical health scales was noteworthy, as was the impact of diabetes on general health, or arthritis on bodily pain scale scores. Arthritis, chronic lung disease and congestive heart failure were the conditions with a higher impact on SF-36 physical summary score, whereas for hypertension and allergies, HRQL impact was low (comparing with a typical person without chronic conditions, deviation scores were around -4 points for the first group and -1 for the second). Differences between chronic conditions in terms of their impact on SF-36 mental summary score were low (deviation scores ranged between -1 and -2). CONCLUSIONS: Arthritis has the highest HRQL impact in the general population of the countries studied due to the combination of a high deviation score on physical scales and a high frequency. Impact of chronic conditions on HRQL was similar roughly across countries, despite important variation in prevalence. The use of HRQL measures such as the SF-36 should be useful to better characterize the global burden of disease.
    Source
    Qual Life Res. 2004 Mar;13(2):283-98. Link to article on publisher's site
    DOI
    10.1023/B:QURE.0000018472.46236.05
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/47457
    PubMed ID
    15085901
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1023/B:QURE.0000018472.46236.05
    Scopus Count
    Collections
    Population and Quantitative Health Sciences Publications

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