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dc.contributor.authorAlonso, Jordi
dc.contributor.authorFerrer, Montserrat
dc.contributor.authorGandek, Barbara
dc.contributor.authorWare, John E. Jr.
dc.contributor.authorAaronson, Neil K.
dc.contributor.authorMosconi, Paola
dc.contributor.authorRasmussen, Niels K.
dc.contributor.authorBullinger, Monika
dc.contributor.authorFukuhara, Shunichi
dc.contributor.authorKaasa, Stein
dc.contributor.authorLeplege, Alain
dc.date2022-08-11T08:10:41.000
dc.date.accessioned2022-08-23T17:16:42Z
dc.date.available2022-08-23T17:16:42Z
dc.date.issued2004-04-17
dc.date.submitted2010-06-18
dc.identifier.citationQual Life Res. 2004 Mar;13(2):283-98. <a href="http://dx.doi.org/10.1023/B:QURE.0000018472.46236.05">Link to article on publisher's site</a>
dc.identifier.issn0962-9343 (Linking)
dc.identifier.doi10.1023/B:QURE.0000018472.46236.05
dc.identifier.pmid15085901
dc.identifier.urihttp://hdl.handle.net/20.500.14038/47457
dc.description.abstractCONTEXT: Few studies and no international comparisons have examined the impact of multiple chronic conditions on populations using a comprehensive health-related quality of life (HRQL) questionnaire. OBJECTIVE: The impact of common chronic conditions on HRQL among the general populations of eight countries was assessed. DESIGN: Cross-sectional mail and interview surveys were conducted. PARTICIPANTS AND SETTING: Sample representatives of the adult general population of eight countries (Denmark, France, Germany, Italy, Japan, The Netherlands, Norway and the United States) were evaluated. Sample sizes ranged from 2031 to 4084. MAIN OUTCOME MEASURES: Self-reported prevalence of chronic conditions (including allergies, arthritis, congestive heart failure, chronic lung disease, hypertension, diabetes, and ischemic heart disease), sociodemographic data and the SF-36 Health Survey were obtained. The SF-36 scale and summary scores were estimated for individuals with and without selected chronic conditions and compared across countries using multivariate linear regression analyses. Adjustments were made for age, gender, marital status, education and the mode of SF-36 administration. RESULTS: More than half (55.1%) of the pooled sample reported at least one chronic condition, and 30.2% had more than one. Hypertension, allergies and arthritis were the most frequently reported conditions. The effect of ischemic heart disease on many of the physical health scales was noteworthy, as was the impact of diabetes on general health, or arthritis on bodily pain scale scores. Arthritis, chronic lung disease and congestive heart failure were the conditions with a higher impact on SF-36 physical summary score, whereas for hypertension and allergies, HRQL impact was low (comparing with a typical person without chronic conditions, deviation scores were around -4 points for the first group and -1 for the second). Differences between chronic conditions in terms of their impact on SF-36 mental summary score were low (deviation scores ranged between -1 and -2). CONCLUSIONS: Arthritis has the highest HRQL impact in the general population of the countries studied due to the combination of a high deviation score on physical scales and a high frequency. Impact of chronic conditions on HRQL was similar roughly across countries, despite important variation in prevalence. The use of HRQL measures such as the SF-36 should be useful to better characterize the global burden of disease.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=15085901&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1023/B:QURE.0000018472.46236.05
dc.subjectAdult
dc.subjectChronic Disease
dc.subjectComorbidity
dc.subjectCross-Cultural Comparison
dc.subjectCross-Sectional Studies
dc.subjectEurope
dc.subjectFemale
dc.subjectHumans
dc.subjectJapan
dc.subjectLinear Models
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPrevalence
dc.subject*Quality of Life
dc.subject*Sickness Impact Profile
dc.subjectUnited States
dc.subjectBiostatistics
dc.subjectEpidemiology
dc.subjectHealth Services Research
dc.titleHealth-related quality of life associated with chronic conditions in eight countries: results from the International Quality of Life Assessment (IQOLA) Project
dc.typeJournal Article
dc.source.journaltitleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
dc.source.volume13
dc.source.issue2
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/qhs_pp/595
dc.identifier.contextkey1363430
html.description.abstract<p>CONTEXT: Few studies and no international comparisons have examined the impact of multiple chronic conditions on populations using a comprehensive health-related quality of life (HRQL) questionnaire.</p> <p>OBJECTIVE: The impact of common chronic conditions on HRQL among the general populations of eight countries was assessed.</p> <p>DESIGN: Cross-sectional mail and interview surveys were conducted.</p> <p>PARTICIPANTS AND SETTING: Sample representatives of the adult general population of eight countries (Denmark, France, Germany, Italy, Japan, The Netherlands, Norway and the United States) were evaluated. Sample sizes ranged from 2031 to 4084.</p> <p>MAIN OUTCOME MEASURES: Self-reported prevalence of chronic conditions (including allergies, arthritis, congestive heart failure, chronic lung disease, hypertension, diabetes, and ischemic heart disease), sociodemographic data and the SF-36 Health Survey were obtained. The SF-36 scale and summary scores were estimated for individuals with and without selected chronic conditions and compared across countries using multivariate linear regression analyses. Adjustments were made for age, gender, marital status, education and the mode of SF-36 administration.</p> <p>RESULTS: More than half (55.1%) of the pooled sample reported at least one chronic condition, and 30.2% had more than one. Hypertension, allergies and arthritis were the most frequently reported conditions. The effect of ischemic heart disease on many of the physical health scales was noteworthy, as was the impact of diabetes on general health, or arthritis on bodily pain scale scores. Arthritis, chronic lung disease and congestive heart failure were the conditions with a higher impact on SF-36 physical summary score, whereas for hypertension and allergies, HRQL impact was low (comparing with a typical person without chronic conditions, deviation scores were around -4 points for the first group and -1 for the second). Differences between chronic conditions in terms of their impact on SF-36 mental summary score were low (deviation scores ranged between -1 and -2).</p> <p>CONCLUSIONS: Arthritis has the highest HRQL impact in the general population of the countries studied due to the combination of a high deviation score on physical scales and a high frequency. Impact of chronic conditions on HRQL was similar roughly across countries, despite important variation in prevalence. The use of HRQL measures such as the SF-36 should be useful to better characterize the global burden of disease.</p>
dc.identifier.submissionpathqhs_pp/595
dc.contributor.departmentDepartment of Quantitative Health Sciences
dc.source.pages283-98


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