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dc.contributor.authorIribarren, Carlos
dc.contributor.authorJacobs, David R.
dc.contributor.authorKiefe, Catarina I.
dc.contributor.authorLewis, Cora E.
dc.contributor.authorMatthews, Karen A.
dc.contributor.authorRoseman, Jeffrey M.
dc.contributor.authorHulley, Stephen B.
dc.date2022-08-11T08:10:42.000
dc.date.accessioned2022-08-23T17:17:16Z
dc.date.available2022-08-23T17:17:16Z
dc.date.issued2004-11-20
dc.date.submitted2010-04-27
dc.identifier.citationSoc Sci Med. 2005 Feb;60(3):471-82. <a href="http://dx.doi.org/10.1016/j.socscimed.2004.06.007">Link to article on publisher's site</a>
dc.identifier.issn0277-9536 (Linking)
dc.identifier.doi10.1016/j.socscimed.2004.06.007
dc.identifier.pmid15550296
dc.identifier.urihttp://hdl.handle.net/20.500.14038/47590
dc.description.abstractWe examined the 16-year mortality experience among participants in the baseline examination (1985-86) of the Coronary Artery Risk Development in Young Adults (CARDIA) Study, a U.S. cohort of 5115 urban adults initially 18-30 years old and balanced by sex and race (black and whites) in the USA. We observed 127 deaths (annual mortality of 0.15%). Compared to white women, the rate ratio (95% confidence interval) of all-cause mortality was 9.3 (4.4, 19.4) among black men, 5.3 (2.5, 11.4) among white men and 2.7 (1.2, 6.1) among black women. The predominant causes of death, which also differed greatly by sex-race, were AIDS (28% of deaths), homicide (16%), unintentional injury (10%), suicide (7%), cancer (7%) and coronary disease (7%). The significant baseline predictors of all-cause mortality in multivariate analysis were male sex, black race, diabetes, self-reported liver and kidney disease, current cigarette smoking and low social support. Two other factors, self-reported thyroid disease and high hostility, were significant predictors in analyses adjusted for age, sex and race. In conclusion, we found striking differences in the rates and underlying cause of death across sex-race groups and several independent predictors of young adult mortality that have major implications for preventive medicine and social policies.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=15550296&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1016/j.socscimed.2004.06.007
dc.subjectAcquired Immunodeficiency Syndrome
dc.subjectCohort Studies
dc.subjectComorbidity
dc.subjectCoronary Disease
dc.subjectFemale
dc.subjectHeart Diseases
dc.subjectHostility
dc.subjectHumans
dc.subject*Life Style
dc.subjectMale
dc.subjectMultivariate Analysis
dc.subjectRisk Factors
dc.subjectSocial Support
dc.subjectSocioeconomic Factors
dc.subjectUrban Population
dc.subjectBioinformatics
dc.subjectBiostatistics
dc.subjectEpidemiology
dc.subjectHealth Services Research
dc.titleCauses and demographic, medical, lifestyle and psychosocial predictors of premature mortality: the CARDIA study
dc.typeJournal Article
dc.source.journaltitleSocial science and medicine (1982)
dc.source.volume60
dc.source.issue3
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/qhs_pp/72
dc.identifier.contextkey1287817
html.description.abstract<p>We examined the 16-year mortality experience among participants in the baseline examination (1985-86) of the Coronary Artery Risk Development in Young Adults (CARDIA) Study, a U.S. cohort of 5115 urban adults initially 18-30 years old and balanced by sex and race (black and whites) in the USA. We observed 127 deaths (annual mortality of 0.15%). Compared to white women, the rate ratio (95% confidence interval) of all-cause mortality was 9.3 (4.4, 19.4) among black men, 5.3 (2.5, 11.4) among white men and 2.7 (1.2, 6.1) among black women. The predominant causes of death, which also differed greatly by sex-race, were AIDS (28% of deaths), homicide (16%), unintentional injury (10%), suicide (7%), cancer (7%) and coronary disease (7%). The significant baseline predictors of all-cause mortality in multivariate analysis were male sex, black race, diabetes, self-reported liver and kidney disease, current cigarette smoking and low social support. Two other factors, self-reported thyroid disease and high hostility, were significant predictors in analyses adjusted for age, sex and race. In conclusion, we found striking differences in the rates and underlying cause of death across sex-race groups and several independent predictors of young adult mortality that have major implications for preventive medicine and social policies.</p>
dc.identifier.submissionpathqhs_pp/72
dc.contributor.departmentDepartment of Quantitative Health Sciences
dc.source.pages471-82


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