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dc.contributor.authorMikuls, Ted R.
dc.contributor.authorCurtis, Jeffrey R.
dc.contributor.authorAllison, Jeroan J.
dc.contributor.authorHicks, Rodney W.
dc.contributor.authorSaag, Kenneth G.
dc.date2022-08-11T08:10:43.000
dc.date.accessioned2022-08-23T17:17:38Z
dc.date.available2022-08-23T17:17:38Z
dc.date.issued2006-02-17
dc.date.submitted2010-08-05
dc.identifier.citationJ Rheumatol. 2006 Mar;33(3):562-6. Epub 2006 Feb 15.
dc.identifier.issn0315-162X (Linking)
dc.identifier.pmid16482645
dc.identifier.urihttp://hdl.handle.net/20.500.14038/47674
dc.description.abstractOBJECTIVE: To more closely assess medication errors in gout care, we examined data from a national, Internet-accessible error reporting program over a 5-year reporting period. METHODS: We examined data from the MEDMARX database, covering the period from January 1, 1999 through December 31, 2003. For allopurinol and colchicine, we examined error severity, source, type, contributing factors, and healthcare personnel involved in errors, and we detailed errors resulting in patient harm. Causes of error and the frequency of other error characteristics were compared for gout medications versus other musculoskeletal treatments using the chi-square statistic. RESULTS: Gout medication errors occurred in 39% (n = 273) of facilities participating in the MEDMARX program. Reported errors were predominantly from the inpatient hospital setting and related to the use of allopurinol (n = 524), followed by colchicine (n = 315), probenecid (n = 50), and sulfinpyrazone (n = 2). Compared to errors involving other musculoskeletal treatments, allopurinol and colchicine errors were more often ascribed to problems with physician prescribing (7% for other therapies versus 23-39% for allopurinol and colchicine, p < 0.0001) and less often due to problems with drug administration or nursing error (50% vs 23-27%, p < 0.0001). CONCLUSION: Our results suggest that inappropriate prescribing practices are characteristic of errors occurring with the use of allopurinol and colchicine. Physician prescribing practices are a potential target for quality improvement interventions in gout care.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=16482645&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://www.jrheum.org/content/33/3/562.full.pdf+html
dc.subject*Adverse Drug Reaction Reporting Systems
dc.subjectAllopurinol
dc.subjectColchicine
dc.subjectGout
dc.subjectGout Suppressants
dc.subjectInternet
dc.subjectMedication Errors
dc.subjectRetrospective Studies
dc.subjectBioinformatics
dc.subjectBiostatistics
dc.subjectEpidemiology
dc.subjectHealth Services Research
dc.titleMedication errors with the use of allopurinol and colchicine: a retrospective study of a national, anonymous Internet-accessible error reporting system
dc.typeJournal Article
dc.source.journaltitleThe Journal of rheumatology
dc.source.volume33
dc.source.issue3
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/qhs_pp/800
dc.identifier.contextkey1426274
html.description.abstract<p>OBJECTIVE: To more closely assess medication errors in gout care, we examined data from a national, Internet-accessible error reporting program over a 5-year reporting period.</p> <p>METHODS: We examined data from the MEDMARX database, covering the period from January 1, 1999 through December 31, 2003. For allopurinol and colchicine, we examined error severity, source, type, contributing factors, and healthcare personnel involved in errors, and we detailed errors resulting in patient harm. Causes of error and the frequency of other error characteristics were compared for gout medications versus other musculoskeletal treatments using the chi-square statistic.</p> <p>RESULTS: Gout medication errors occurred in 39% (n = 273) of facilities participating in the MEDMARX program. Reported errors were predominantly from the inpatient hospital setting and related to the use of allopurinol (n = 524), followed by colchicine (n = 315), probenecid (n = 50), and sulfinpyrazone (n = 2). Compared to errors involving other musculoskeletal treatments, allopurinol and colchicine errors were more often ascribed to problems with physician prescribing (7% for other therapies versus 23-39% for allopurinol and colchicine, p < 0.0001) and less often due to problems with drug administration or nursing error (50% vs 23-27%, p < 0.0001).</p> <p>CONCLUSION: Our results suggest that inappropriate prescribing practices are characteristic of errors occurring with the use of allopurinol and colchicine. Physician prescribing practices are a potential target for quality improvement interventions in gout care.</p>
dc.identifier.submissionpathqhs_pp/800
dc.contributor.departmentDepartment of Quantitative Health Sciences
dc.source.pages562-6


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