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dc.contributor.authorFitzgerald, Thomas J.
dc.contributor.authorBishop-Jodoin, Maryann
dc.contributor.authorLaurie, Fran
dc.contributor.authorUlin, Kenneth
dc.contributor.authorMoni, Janaki
dc.contributor.authorCicchetti, Maria Giulia
dc.date2022-08-11T08:10:46.000
dc.date.accessioned2022-08-23T17:19:01Z
dc.date.available2022-08-23T17:19:01Z
dc.date.issued2018-11-15
dc.date.submitted2019-01-16
dc.identifier.citation<p>Int J Radiat Oncol Biol Phys. 2018 Nov 15;102(4):775-782. doi: 10.1016/j.ijrobp.2018.08.039. Epub 2018 Oct 18. <a href="https://doi.org/10.1016/j.ijrobp.2018.08.039">Link to article on publisher's site</a></p>
dc.identifier.issn0360-3016 (Linking)
dc.identifier.doi10.1016/j.ijrobp.2018.08.039
dc.identifier.pmid30353882
dc.identifier.urihttp://hdl.handle.net/20.500.14038/47982
dc.description<p>Full author list omitted for brevity. For the full list of authors, see article.</p>
dc.description.abstractImaging is essential in successfully executing radiation therapy (RT) in oncology clinical trials. As technically sophisticated diagnostic imaging and RT were incorporated into trials, quality assurance in the National Clinical Trials Network groups entered a new era promoting image acquisition and review. Most trials involving RT require pre- and post-therapy imaging for target validation and outcome assessment. The increasing real-time (before and during therapy) imaging and RT object reviews are to ensure compliance with trial objectives. Objects easily transmit digitally for review from anywhere in the world. Physician interpretation of imaging and image application to RT treatment plans is essential for optimal trial execution. Imaging and RT data sets are used to credential RT sites to confirm investigator and institutional ability to meet trial target volume delineation and delivery requirements. Real-time imaging and RT object reviews can be performed multiple times during a trial to assess response to therapy and application of RT objects. This process has matured into an effective data management mechanism. When necessary, site and study investigators review objects together through web media technologies to ensure the patient is enrolled on the appropriate trial and the intended RT is planned and executed in a trial-compliant manner. Real-time imaging review makes sure: (1) the patient is entered and eligible for the trial, (2) the patient meets trial-specific adaptive therapy requirements, if applicable, and (3) the intended RT is according to trial guidelines. This review ensures the study population is uniform and the results are believable and can be applied to clinical practice.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=30353882&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510266/
dc.subjectNeoplasms
dc.subjectOncology
dc.subjectRadiation Medicine
dc.subjectRadiology
dc.titleThe Importance of Imaging in Radiation Oncology for National Clinical Trials Network Protocols
dc.typeJournal Article
dc.source.journaltitleInternational journal of radiation oncology, biology, physics
dc.source.volume102
dc.source.issue4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/radiationoncology_pubs/91
dc.identifier.contextkey13633524
html.description.abstract<p>Imaging is essential in successfully executing radiation therapy (RT) in oncology clinical trials. As technically sophisticated diagnostic imaging and RT were incorporated into trials, quality assurance in the National Clinical Trials Network groups entered a new era promoting image acquisition and review. Most trials involving RT require pre- and post-therapy imaging for target validation and outcome assessment. The increasing real-time (before and during therapy) imaging and RT object reviews are to ensure compliance with trial objectives. Objects easily transmit digitally for review from anywhere in the world. Physician interpretation of imaging and image application to RT treatment plans is essential for optimal trial execution. Imaging and RT data sets are used to credential RT sites to confirm investigator and institutional ability to meet trial target volume delineation and delivery requirements. Real-time imaging and RT object reviews can be performed multiple times during a trial to assess response to therapy and application of RT objects. This process has matured into an effective data management mechanism. When necessary, site and study investigators review objects together through web media technologies to ensure the patient is enrolled on the appropriate trial and the intended RT is planned and executed in a trial-compliant manner. Real-time imaging review makes sure: (1) the patient is entered and eligible for the trial, (2) the patient meets trial-specific adaptive therapy requirements, if applicable, and (3) the intended RT is according to trial guidelines. This review ensures the study population is uniform and the results are believable and can be applied to clinical practice.</p>
dc.identifier.submissionpathradiationoncology_pubs/91
dc.contributor.departmentDepartment of Radiation Oncology
dc.contributor.departmentQuality Assurance Review Center
dc.contributor.departmentImaging and Radiation Oncology Core
dc.source.pages775-782


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