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dc.contributor.authorMayasi, Yunis M
dc.contributor.authorTakhtani, Deepak
dc.contributor.authorGarg, Neeta
dc.date2022-08-11T08:10:46.000
dc.date.accessioned2022-08-23T17:19:11Z
dc.date.available2022-08-23T17:19:11Z
dc.date.issued2014-12-11
dc.date.submitted2015-03-11
dc.identifier.citation<p>Neurol Neuroimmunol Neuroinflamm. 2014 Dec 11;1(4):e51. doi: 10.1212/NXI.0000000000000051. eCollection 2014 Dec. <a href="http://dx.doi.org/10.1212/NXI.0000000000000051">Link to article on publisher's site</a></p>
dc.identifier.issn2332-7812 (Linking)
dc.identifier.doi10.1212/NXI.0000000000000051
dc.identifier.pmid25520958
dc.identifier.urihttp://hdl.handle.net/20.500.14038/48013
dc.description.abstractOBJECTIVE: To describe a case of leucine-rich glioma-inactivated protein 1 (LGI1) antibody-associated encephalitis. METHODS: The clinical and ancillary data and brain MRIs were gathered retrospectively by chart review. Relevant literature on similar cases was also reviewed. RESULTS: The diagnosis of LGI1 antibody-associated autoimmune encephalitis was based on the typical clinical presentation of seizures, psychiatric symptoms, and memory loss as well as negative diagnostic testing for cancer; the diagnosis was confirmed by positive LGI1 antibody. The patient responded favorably to treatment with IV immunoglobulin and continues to do well. CONCLUSION: LGI1 antibody-associated encephalitis has increasingly been recognized as a primary autoimmune disorder with good prognosis and response to treatment.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=25520958&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttp://dx.doi.org/10.1212/NXI.0000000000000051
dc.rightsCopyright © 2014 American Academy of Neurology. This is an open access article distributed under the terms of the Creative Commons Attribution-Noncommercial No Derivative 3.0 License, which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially.
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subjectImmune System Diseases
dc.subjectNervous System Diseases
dc.subjectNeurology
dc.subjectRadiology
dc.titleLeucine-rich glioma-inactivated protein 1 antibody encephalitis: A case report
dc.typeJournal Article
dc.source.journaltitleNeurology(R) neuroimmunology and neuroinflammation
dc.source.volume1
dc.source.issue4
dc.identifier.legacyfulltexthttps://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1130&amp;context=radiology_pubs&amp;unstamped=1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/radiology_pubs/120
dc.identifier.contextkey6817962
refterms.dateFOA2022-08-23T17:19:11Z
html.description.abstract<p>OBJECTIVE: To describe a case of leucine-rich glioma-inactivated protein 1 (LGI1) antibody-associated encephalitis.</p> <p>METHODS: The clinical and ancillary data and brain MRIs were gathered retrospectively by chart review. Relevant literature on similar cases was also reviewed.</p> <p>RESULTS: The diagnosis of LGI1 antibody-associated autoimmune encephalitis was based on the typical clinical presentation of seizures, psychiatric symptoms, and memory loss as well as negative diagnostic testing for cancer; the diagnosis was confirmed by positive LGI1 antibody. The patient responded favorably to treatment with IV immunoglobulin and continues to do well.</p> <p>CONCLUSION: LGI1 antibody-associated encephalitis has increasingly been recognized as a primary autoimmune disorder with good prognosis and response to treatment.</p>
dc.identifier.submissionpathradiology_pubs/120
dc.contributor.departmentDepartment of Radiology
dc.contributor.departmentDepartment of Neurology
dc.source.pagese51


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Copyright © 2014 American Academy of Neurology. This is an open access article distributed under the terms of the Creative Commons Attribution-Noncommercial No Derivative 3.0 License, which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially.
Except where otherwise noted, this item's license is described as Copyright © 2014 American Academy of Neurology. This is an open access article distributed under the terms of the Creative Commons Attribution-Noncommercial No Derivative 3.0 License, which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially.