Hepatocellular carcinoma recurrence pattern following liver transplantation and a suggested surveillance algorithm
Karam, Adib R.
Barry, Curtis T.
UMass Chan AffiliationsDepartment of Medicine, Division of Gastroenterology
Department of Surgery
Department of Radiation Oncology
Department of Radiology
Digestive System Diseases
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AbstractPurpose: Evaluate the recurrence pattern of hepatocellular carcinoma (HCC) following liver transplantation. Materials and Methods: A total of 54 patients underwent liver transplantation for HCC; 9 patients developed biopsy proven recurrent HCC (16.6%). The site of HCC recurrence along with other factors were analyzed. Results: Seven patients were diagnosed with HCC prior to liver transplantation and 2 patients had incidental HCC in the explanted liver. Two patients had locoregional recurrence, 4 patients had distant metastasis and 3 patients had synchronous locoregional recurrence and distant metastasis. Conclusion: A significant proportion of HCC recurrence following liver transplantation is extrahepatic.
SourceScortegagna E Jr, Karam AR, Sioshansi S, Bozorgzadeh A, Barry C, Hussain S. Hepatocellular carcinoma recurrence pattern following liver transplantation and a suggested surveillance algorithm. Clin Imaging. 2016 Jul 7;40(6):1131-1134. doi: 10.1016/j.clinimag.2016.07.002. [Epub ahead of print] PubMed PMID: 27474913.
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/48074
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