Hepatocellular carcinoma recurrence pattern following liver transplantation and a suggested surveillance algorithm
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Authors
Scortegagna, EduardoKaram, Adib R.
Sioshansi, Shirin
Bozorgzadeh, Adel
Barry, Curtis T.
Hussain, Sarwat
UMass Chan Affiliations
Department of Medicine, Division of GastroenterologyDepartment of Surgery
Department of Radiation Oncology
Department of Radiology
Document Type
Journal ArticlePublication Date
2016-07-07Keywords
Hepatocellular carcinomaHCC
Liver transplantation
surveillance
metastasis
Digestive System Diseases
Gastroenterology
Hepatology
Neoplasms
Oncology
Radiology
Surgery
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Show full item recordAbstract
Purpose: Evaluate the recurrence pattern of hepatocellular carcinoma (HCC) following liver transplantation. Materials and Methods: A total of 54 patients underwent liver transplantation for HCC; 9 patients developed biopsy proven recurrent HCC (16.6%). The site of HCC recurrence along with other factors were analyzed. Results: Seven patients were diagnosed with HCC prior to liver transplantation and 2 patients had incidental HCC in the explanted liver. Two patients had locoregional recurrence, 4 patients had distant metastasis and 3 patients had synchronous locoregional recurrence and distant metastasis. Conclusion: A significant proportion of HCC recurrence following liver transplantation is extrahepatic.Source
Scortegagna E Jr, Karam AR, Sioshansi S, Bozorgzadeh A, Barry C, Hussain S. Hepatocellular carcinoma recurrence pattern following liver transplantation and a suggested surveillance algorithm. Clin Imaging. 2016 Jul 7;40(6):1131-1134. doi: 10.1016/j.clinimag.2016.07.002. [Epub ahead of print] PubMed PMID: 27474913.DOI
10.1016/j.clinimag.2016.07.002Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48074PubMed ID
27474913Related Resources
Link to article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/j.clinimag.2016.07.002