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    Proceedings of the third international molecular pathological epidemiology (MPE) meeting

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    Authors
    Campbell, P. T.
    Bogdanov, Alexei A. Jr.
    Ogino, Shuji
    UMass Chan Affiliations
    Department of Radiology
    Document Type
    Journal Article
    Publication Date
    2017-02-01
    Keywords
    Meeting report
    Molecular pathological epidemiology
    Proceedings
    Epidemiology
    Neoplasms
    Pathology
    Radiology
    
    Metadata
    Show full item record
    Link to Full Text
    https://doi.org/10.1007/s10552-016-0845-z
    Abstract
    Molecular pathological epidemiology (MPE) is a transdisciplinary and relatively new scientific discipline that integrates theory, methods, and resources from epidemiology, pathology, biostatistics, bioinformatics, and computational biology. The underlying objective of MPE research is to better understand the etiology and progression of complex and heterogeneous human diseases with the goal of informing prevention and treatment efforts in population health and clinical medicine. Although MPE research has been commonly applied to investigating breast, lung, and colorectal cancers, its methodology can be used to study most diseases. Recent successes in MPE studies include: (1) the development of new statistical methods to address etiologic heterogeneity; (2) the enhancement of causal inference; (3) the identification of previously unknown exposure-subtype disease associations; and (4) better understanding of the role of lifestyle/behavioral factors on modifying prognosis according to disease subtype. Central challenges to MPE include the relative lack of transdisciplinary experts, educational programs, and forums to discuss issues related to the advancement of the field. To address these challenges, highlight recent successes in the field, and identify new opportunities, a series of MPE meetings have been held at the Dana-Farber Cancer Institute in Boston, MA. Herein, we share the proceedings of the Third International MPE Meeting, held in May 2016 and attended by 150 scientists from 17 countries. Special topics included integration of MPE with immunology and health disparity research. This meeting series will continue to provide an impetus to foster further transdisciplinary integration of divergent scientific fields.
    Source
    Cancer Causes Control. 2017 Feb;28(2):167-176. Epub 2017 Jan 17. Link to article on publisher's site
    DOI
    10.1007/s10552-016-0845-z
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/48103
    PubMed ID
    28097472
    Notes

    Full author list omitted for brevity. For the full list of authors, see article.

    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10552-016-0845-z
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