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dc.contributor.authorSchaub, Steven
dc.contributor.authorSirkis, Hartley M.
dc.contributor.authorKay, Jonathan
dc.date2022-08-11T08:10:46.000
dc.date.accessioned2022-08-23T17:19:36Z
dc.date.available2022-08-23T17:19:36Z
dc.date.issued2016-11-01
dc.date.submitted2017-05-08
dc.identifier.citationRheum Dis Clin North Am. 2016 Nov;42(4):695-710. doi: 10.1016/j.rdc.2016.07.011. <a href="https://doi.org/10.1016/j.rdc.2016.07.011">Link to article on publisher's site</a>
dc.identifier.issn0889-857X (Linking)
dc.identifier.doi10.1016/j.rdc.2016.07.011
dc.identifier.pmid27742022
dc.identifier.urihttp://hdl.handle.net/20.500.14038/48110
dc.description.abstractMultifocal osteomyelitis and synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome constitute a spectrum of disease that includes inflammatory bone lesions and dermatologic findings. Radiographic features resemble those of the spondyloarthropathies with anterior chest wall involvement. Early radiographic findings are osteodestructive with lytic lesions. Bone scintigraphy of the sternoclavicular region classically yields a 'bull's head' pattern of radionuclide uptake. Magnetic resonance imaging (MRI) can demonstrate corner lesions of vertebral bodies. Ultrasound often reveals peripheral enthesitis. Late radiographic features are usually osteoproliferative. PET/CT can identify chronic lesions. Differential diagnostic considerations include osteomyelitis and malignancy, which often prompt bone biopsy.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=27742022&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttps://doi.org/10.1016/j.rdc.2016.07.011
dc.subjectAcne
dc.subjectCRMO
dc.subjectHyperostosis
dc.subjectOsteitis
dc.subjectPalmoplantar pustulosis
dc.subjectSAPHO syndrome
dc.subjectVertebral corner lesion
dc.subject‘Bull's head’ sign
dc.subjectDermatology
dc.subjectRadiology
dc.subjectRheumatology
dc.titleImaging for Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome
dc.typeJournal Article
dc.source.journaltitleRheumatic diseases clinics of North America
dc.source.volume42
dc.source.issue4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/radiology_pubs/215
dc.identifier.contextkey10133381
html.description.abstract<p>Multifocal osteomyelitis and synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome constitute a spectrum of disease that includes inflammatory bone lesions and dermatologic findings. Radiographic features resemble those of the spondyloarthropathies with anterior chest wall involvement. Early radiographic findings are osteodestructive with lytic lesions. Bone scintigraphy of the sternoclavicular region classically yields a 'bull's head' pattern of radionuclide uptake. Magnetic resonance imaging (MRI) can demonstrate corner lesions of vertebral bodies. Ultrasound often reveals peripheral enthesitis. Late radiographic features are usually osteoproliferative. PET/CT can identify chronic lesions. Differential diagnostic considerations include osteomyelitis and malignancy, which often prompt bone biopsy.</p>
dc.identifier.submissionpathradiology_pubs/215
dc.contributor.departmentDepartment of Radiology
dc.contributor.departmentDepartment of Medicine, Division of Rheumatology
dc.source.pages695-710


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