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    Evaluation of Rigid-Body Motion Compensation in Cardiac Perfusion SPECT Employing Polar-Map Quantification

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    Authors
    Pretorius, P. Hendrik
    Johnson, Karen L.
    King, Michael A.
    UMass Chan Affiliations
    Department of Radiology
    Document Type
    Journal Article
    Publication Date
    2016-06-01
    Keywords
    Cardiac Imaging
    Motion Correction
    SPECT
    Radiology
    
    Metadata
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    Link to Full Text
    https://doi.org/10.1109/TNS.2016.2545407
    Abstract
    We have recently been successful in the development and testing of rigid-body motion tracking, estimation and compensation for cardiac perfusion SPECT based on a visual tracking system (VTS). The goal of this study was to evaluate in patients the effectiveness of our rigid-body motion compensation strategy. Sixty-four patient volunteers were asked to remain motionless or execute some predefined body motion during an additional second stress perfusion acquisition. Acquisitions were performed using the standard clinical protocol with 64 projections acquired through 180 degrees. All data were reconstructed with an ordered-subsets expectation-maximization (OSEM) algorithm using 4 projections per subset and 5 iterations. All physical degradation factors were addressed (attenuation, scatter, and distance dependent resolution), while a 3-dimensional Gaussian rotator was used during reconstruction to correct for six-degree-of-freedom (6-DOF) rigid-body motion estimated by the VTS. Polar map quantification was employed to evaluate compensation techniques. In 54.7% of the uncorrected second stress studies there was a statistically significant difference in the polar maps, and in 45.3% this made a difference in the interpretation of segmental perfusion. Motion correction reduced the impact of motion such that with it 32.8 % of the polar maps were statistically significantly different, and in 14.1% this difference changed the interpretation of segmental perfusion. The improvement shown in polar map quantitation translated to visually improved uniformity of the SPECT slices.
    Source
    IEEE Trans Nucl Sci. 2016 Jun;63(3):1419-1425. Epub 2016 Jun 24. Link to article on publisher's site
    DOI
    10.1109/TNS.2016.2545407
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/48124
    PubMed ID
    28042170
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1109/TNS.2016.2545407
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