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dc.contributor.authorPretorius, P. Hendrik
dc.contributor.authorJohnson, Karen L.
dc.contributor.authorKing, Michael A.
dc.date2022-08-11T08:10:46.000
dc.date.accessioned2022-08-23T17:19:39Z
dc.date.available2022-08-23T17:19:39Z
dc.date.issued2016-06-01
dc.date.submitted2017-05-15
dc.identifier.citationIEEE Trans Nucl Sci. 2016 Jun;63(3):1419-1425. Epub 2016 Jun 24. <a href="https://doi.org/10.1109/TNS.2016.2545407">Link to article on publisher's site</a>
dc.identifier.issn0018-9499 (Linking)
dc.identifier.doi10.1109/TNS.2016.2545407
dc.identifier.pmid28042170
dc.identifier.urihttp://hdl.handle.net/20.500.14038/48124
dc.description.abstractWe have recently been successful in the development and testing of rigid-body motion tracking, estimation and compensation for cardiac perfusion SPECT based on a visual tracking system (VTS). The goal of this study was to evaluate in patients the effectiveness of our rigid-body motion compensation strategy. Sixty-four patient volunteers were asked to remain motionless or execute some predefined body motion during an additional second stress perfusion acquisition. Acquisitions were performed using the standard clinical protocol with 64 projections acquired through 180 degrees. All data were reconstructed with an ordered-subsets expectation-maximization (OSEM) algorithm using 4 projections per subset and 5 iterations. All physical degradation factors were addressed (attenuation, scatter, and distance dependent resolution), while a 3-dimensional Gaussian rotator was used during reconstruction to correct for six-degree-of-freedom (6-DOF) rigid-body motion estimated by the VTS. Polar map quantification was employed to evaluate compensation techniques. In 54.7% of the uncorrected second stress studies there was a statistically significant difference in the polar maps, and in 45.3% this made a difference in the interpretation of segmental perfusion. Motion correction reduced the impact of motion such that with it 32.8 % of the polar maps were statistically significantly different, and in 14.1% this difference changed the interpretation of segmental perfusion. The improvement shown in polar map quantitation translated to visually improved uniformity of the SPECT slices.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=28042170&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttps://doi.org/10.1109/TNS.2016.2545407
dc.subjectCardiac Imaging
dc.subjectMotion Correction
dc.subjectSPECT
dc.subjectRadiology
dc.titleEvaluation of Rigid-Body Motion Compensation in Cardiac Perfusion SPECT Employing Polar-Map Quantification
dc.typeJournal Article
dc.source.journaltitleIEEE transactions on nuclear science
dc.source.volume63
dc.source.issue3
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/radiology_pubs/230
dc.identifier.contextkey10166376
html.description.abstract<p>We have recently been successful in the development and testing of rigid-body motion tracking, estimation and compensation for cardiac perfusion SPECT based on a visual tracking system (VTS). The goal of this study was to evaluate in patients the effectiveness of our rigid-body motion compensation strategy. Sixty-four patient volunteers were asked to remain motionless or execute some predefined body motion during an additional second stress perfusion acquisition. Acquisitions were performed using the standard clinical protocol with 64 projections acquired through 180 degrees. All data were reconstructed with an ordered-subsets expectation-maximization (OSEM) algorithm using 4 projections per subset and 5 iterations. All physical degradation factors were addressed (attenuation, scatter, and distance dependent resolution), while a 3-dimensional Gaussian rotator was used during reconstruction to correct for six-degree-of-freedom (6-DOF) rigid-body motion estimated by the VTS. Polar map quantification was employed to evaluate compensation techniques. In 54.7% of the uncorrected second stress studies there was a statistically significant difference in the polar maps, and in 45.3% this made a difference in the interpretation of segmental perfusion. Motion correction reduced the impact of motion such that with it 32.8 % of the polar maps were statistically significantly different, and in 14.1% this difference changed the interpretation of segmental perfusion. The improvement shown in polar map quantitation translated to visually improved uniformity of the SPECT slices.</p>
dc.identifier.submissionpathradiology_pubs/230
dc.contributor.departmentDepartment of Radiology
dc.source.pages1419-1425


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