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dc.contributor.authorSpilberg, Gabriela
dc.contributor.authorCarniato, Sarena L.
dc.contributor.authorKing, R. M.
dc.contributor.authorvan der Bom, Imramsjah M. J.
dc.contributor.authorMehra, Manik
dc.contributor.authorWalvick, Ronn P.
dc.contributor.authorWakhloo, Ajay K.
dc.contributor.authorGounis, Matthew J.
dc.date2022-08-11T08:10:47.000
dc.date.accessioned2022-08-23T17:19:55Z
dc.date.available2022-08-23T17:19:55Z
dc.date.issued2012-04-01
dc.date.submitted2017-06-19
dc.identifier.citationAJNR Am J Neuroradiol. 2012 Apr;33(4):655-60. Epub 2011 Dec 22. <a href="https://doi.org/10.3174/ajnr.A2831">Link to article on publisher's site</a>
dc.identifier.issn0195-6108 (Linking)
dc.identifier.doi10.3174/ajnr.A2831
dc.identifier.pmid22194374
dc.identifier.urihttp://hdl.handle.net/20.500.14038/48188
dc.description.abstractBACKGROUND AND PURPOSE: Intracranial aneurysms treated by coiling have a risk for recurrence, requiring surveillance imaging. MRA has emerged as an attractive technique for postcoiling aneurysm imaging. Previous research has evaluated MR imaging artifacts of the coil mass in vitro. Our aim in this study was to evaluate MR imaging artifacts of coiled aneurysms in vivo with time. MATERIALS AND METHODS: Four sidewall aneurysms were created in each of 4 dogs. Aneurysms were embolized receiving only 1 type of coils. After embolization, the animals were transferred to MR imaging, which included axial 3D TOF MRA (TEs, 3.5, 5, and 6.9 ms), phase-contrast MRA, and coronal CE-MRA. MR imaging studies were repeated at 1, 4, 6, 8, 14, and 28 weeks. We calculated an OEF: OEF = V(A)/V(CM), where the numerator represents the volume of the MR imaging artifacts and the denominator is the true volume of the coil mass measured by 3D RA. RESULTS: OEFs were largest immediately after embolization and showed a gradual decay until approximately 4 weeks, when there was stabilization of the size of the artifacts. By 4 weeks, there was mild coil compaction (average coil mass volume decrease of 7.8%); however, the OEFs decreased by 25% after 4 weeks (P < .001). CONCLUSIONS: MR imaging susceptibility artifacts change with time, being maximal in the postembolization setting and decaying until 4 weeks. The clinical implications of this study are that baseline MRA for comparison with future imaging should be acquired at a minimum of 1 week after the procedure.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=22194374&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttps://doi.org/10.3174/ajnr.A2831
dc.subjectNeurology
dc.subjectRadiology
dc.titleTemporal evolution of susceptibility artifacts from coiled aneurysms on MR angiography: an in vivo canine study
dc.typeJournal Article
dc.source.journaltitleAJNR. American journal of neuroradiology
dc.source.volume33
dc.source.issue4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/radiology_pubs/303
dc.identifier.contextkey10320043
html.description.abstract<p>BACKGROUND AND PURPOSE: Intracranial aneurysms treated by coiling have a risk for recurrence, requiring surveillance imaging. MRA has emerged as an attractive technique for postcoiling aneurysm imaging. Previous research has evaluated MR imaging artifacts of the coil mass in vitro. Our aim in this study was to evaluate MR imaging artifacts of coiled aneurysms in vivo with time.</p> <p>MATERIALS AND METHODS: Four sidewall aneurysms were created in each of 4 dogs. Aneurysms were embolized receiving only 1 type of coils. After embolization, the animals were transferred to MR imaging, which included axial 3D TOF MRA (TEs, 3.5, 5, and 6.9 ms), phase-contrast MRA, and coronal CE-MRA. MR imaging studies were repeated at 1, 4, 6, 8, 14, and 28 weeks. We calculated an OEF: OEF = V(A)/V(CM), where the numerator represents the volume of the MR imaging artifacts and the denominator is the true volume of the coil mass measured by 3D RA.</p> <p>RESULTS: OEFs were largest immediately after embolization and showed a gradual decay until approximately 4 weeks, when there was stabilization of the size of the artifacts. By 4 weeks, there was mild coil compaction (average coil mass volume decrease of 7.8%); however, the OEFs decreased by 25% after 4 weeks (P < .001).</p> <p>CONCLUSIONS: MR imaging susceptibility artifacts change with time, being maximal in the postembolization setting and decaying until 4 weeks. The clinical implications of this study are that baseline MRA for comparison with future imaging should be acquired at a minimum of 1 week after the procedure.</p>
dc.identifier.submissionpathradiology_pubs/303
dc.contributor.departmentNew England Center for Stroke Research
dc.contributor.departmentDepartment of Radiology
dc.source.pages655-60


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