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    Pipeline Embolization Device for Pericallosal Artery Aneurysms: A Retrospective Single Center Safety and Efficacy Study

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    Authors
    de Macedo Rodrigues, Katyucia
    Kuhn, Anna L.
    Tamura, Takamitsu
    Dabus, Guilherme
    Kan, Peter
    Marosfoi, Miklos G.
    Lozano, Juan Diego
    Perras, Mary
    Brooks, Christopher
    Howk, Mary
    Hou, Samuel Y.
    Rex, David E.
    Massari, Francesco
    Gounis, Matthew J.
    Wakhloo, Ajay K.
    Puri, Ajit S.
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    UMass Chan Affiliations
    New England Center for Stroke Research
    Department of Radiology, Division of Neuroimaging and Intervention
    Document Type
    Journal Article
    Publication Date
    2017-05-17
    Keywords
    aneurysm
    artery
    flow diverter
    pericallosal
    Neurology
    Radiology
    
    Metadata
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    Link to Full Text
    https://doi.org/10.1093/ons/opx111
    Abstract
    BACKGROUND: Pericallosal artery aneurysm treatment may be challenging using traditional endovascular techniques. OBJECTIVE: To demonstrate the feasibility, efficacy, and safety of endovascular treatment of pericallosal artery aneurysm using flow diverters. METHODS: We performed a retrospective review of our institutional database from July 2013 through July 2016 and identified 7 subjects with a pericallosal artery aneurysm treated with the Pipeline embolization device (ev3 Neurovascular, Medtronic, Dublin, Ireland) and at least 1 follow-up angiogram. Technical feasibility, procedural complication, angiographic results, and clinical outcome were evaluated. RESULTS: Placement of the Pipeline embolization device was successful in all cases without evidence of procedural complication. Five out of 7 subjects showed a complete aneurysm occlusion at 6- to 12-mo follow-up angiogram. The 2 subjects with persistent aneurysm filling showed decreased aneurysm sac volume on follow-up angiograms (96% and 60%). There was no evidence of in-implant stenosis or intimal hyperplasia. No thromboembolic or hemorrhagic complications were seen during the follow-up period. Only 1 patient had a transient change in Modified Rankin scale score from baseline as a result of different unrelated procedure. CONCLUSION: Our preliminary results demonstrate feasibility of the use of flow diverter stent for treatment of aneurysms of the pericallosal artery with rate of aneurysm occlusion comparable to literature and without evidence of increased procedural or short-term morbidity. A long-term and larger cohort study is needed to validate our findings.
    Source
    Oper Neurosurg (Hagerstown). 2017 May 17. doi: 10.1093/ons/opx111. Link to article on publisher's site
    DOI
    10.1093/ons/opx111
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/48203
    PubMed ID
    28521024
    Related Resources
    Link to Article in PubMed
    ae974a485f413a2113503eed53cd6c53
    10.1093/ons/opx111
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