Investigation of the physical effects of respiratory motion compensation in a large population of patients undergoing Tc-99m cardiac perfusion SPECT/CT stress imaging
UMass Chan Affiliations
Department of RadiologyDocument Type
Journal ArticlePublication Date
2017-04-21Keywords
Cardiac perfusionMotion tracking
Respiratory motion estimation and correction
SPECT/CT
Cardiology
Radiology
Metadata
Show full item recordAbstract
BACKGROUND: Respiratory motion can deteriorate image fidelity in cardiac perfusion SPECT. We determined the extent of respiratory motion, assessed its impact on image fidelity, and investigated the existence of gender differences, thereby examining the influence of respiratory motion in a large population of patients. METHODS: One thousand one hundred and three SPECT/CT patients underwent visual tracking of markers on their anterior surface during stress acquisition to track respiratory motion. The extent of motion was estimated by registration. Visual indicators of changes in cardiac slices with motion correction, and the correlation between the extent of motion with changes in segmental-counts were assessed. RESULTS: Respiratory motion in the head-to-feet direction was the largest component of motion, varying between 1.1 and 37.4 mm, and was statistically significantly higher (p = 0.002) for males than females. In 33.0% of the patients, motion estimates were larger than 10 mm. Patients progressively show more distinct visual changes with an increase in the extent of motion. The increase in segmental-count differences in the anterior, antero-lateral, and inferior segments correlated with the extent of motion. CONCLUSIONS: Respiratory motion correction diminished the artefactual reduction in anterior and inferior wall counts associated with respiratory motion. The extent of improvement was strongly related to the magnitude of motion.Source
J Nucl Cardiol. 2017 Apr 21. doi: 10.1007/s12350-017-0890-3. Link to article on publisher's siteDOI
10.1007/s12350-017-0890-3Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48216PubMed ID
28432671Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1007/s12350-017-0890-3