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    Novel Distal Emboli Protection Technology: The EmboTrap

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    Authors
    Chueh, Juyu
    Marosfoi, Miklos G.
    Brooks, Olivia W.
    King, Robert M.
    Puri, Ajit S.
    Gounis, Matthew J.
    UMass Chan Affiliations
    New England Center for Stroke Research, Department of Radiology
    Document Type
    Journal Article
    Publication Date
    2017-10-01
    Keywords
    Acute stroke
    Embolization
    Endovascular stroke therapy
    Revascularization
    Stroke thrombectomy
    Cardiovascular Diseases
    Equipment and Supplies
    Nervous System Diseases
    Radiology
    Surgery
    
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    Link to Full Text
    https://doi.org/10.1159/000480668
    Abstract
    Background: Over the course of the thrombectomy procedure, clot fragments may become dislodged and lead to downstream emboli due to manipulation of an endovascular device. The EmboTrap thrombectomy system features an inner stent channel with an outer stent trap design that may potentially reduce the risk of distal clot fragmentation during clot removal. We tested the hypothesis that distal emboli to both the same and new territory generated during mechanical thrombectomy are a function of device design. Methods: EmboTrap and Solitaire thrombectomy were conducted in an in vitro model system that mimicked a middle-cerebral artery (MCA) occlusion within a complete circle of Willis vascular replica and a contrast-enhanced clot analog. Emboli generated during the procedure with a size > 1,000 mum were collected and measured with calipers. The Coulter principle was used to characterize emboli with a size between 200 and 1,000 microm. Results: EmboTrap thrombectomy resulted in a significant reduction in the risk of large emboli ( > 1,000 mum) formation as compared to first-generation stent retriever thrombectomy (p = 0.031, Fisher exact test). The majority of emboli > 1,000 mum ( approximately 80%) were found in the MCA, regardless of device type. There was no significant difference between the EmboTrap and Solitaire in 200 to 1,000 mum emboli formation (p = 0.89, Mann-Whitney test). When combining all emboli in the most dangerous range ( > 200 mum), EmboTrap offered a size reduction of emboli (p = 0.022). Conclusion: The risk of distal embolization can be altered with improved stent retriever design. When encountering fragment-prone clots, EmboTrap thrombectomy may lower the risk of distal embolization.
    Source
    Interv Neurol. 2017 Oct;6(3-4):268-276. doi: 10.1159/000480668. Epub 2017 Sep 16. Link to article on publisher's site
    DOI
    10.1159/000480668
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/48256
    PubMed ID
    29118805
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    Link to Article in PubMed

    ae974a485f413a2113503eed53cd6c53
    10.1159/000480668
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