Authors
Luna, Elizabeth J.Document Type
Journal ArticlePublication Date
2019-05-03Keywords
myosinmyosin 18A
myosin 18B
muscle
Amino Acids, Peptides, and Proteins
Biochemistry
Cell Biology
Cells
Cellular and Molecular Physiology
Developmental Biology
Musculoskeletal System
Metadata
Show full item recordAbstract
"Myosin" is famous as a component of muscle fibrils, but the majority of myosin family members act elsewhere with roles unrelated to muscle contraction. The biological functions of a relatively new family of these unconventional myosins, myosins 18A and 18B, are poorly understood. New research from Horsthemke et al. describes a new isoform (Myo18Agamma) that is essential for heart function and viability in mice. Their findings both support and contradict other work in the field and raise new questions about the roles of myosin 18 proteins in vivo.Source
This research was originally published in: J Biol Chem. 2019 May 3;294(18):7219-7220. doi: 10.1074/jbc.H119.008784. Link to article on publisher's site
DOI
10.1074/jbc.H119.008784Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48361PubMed ID
31053679Related Resources
Rights
© 2019 Luna. Publisher's PDF posted after 12 months as allowed by the publisher's author rights policy at http://www.jbc.org/site/misc/edpolicy.xhtml#copyright.ae974a485f413a2113503eed53cd6c53
10.1074/jbc.H119.008784