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    Introduction. Formation, growth, and rupture: the biology and physics of cerebral aneurysms

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    Authors
    Prestigiacomo, Charles J.
    Gounis, Matthew J.
    Gonzalez, L. Fernando
    Frosen, Juhana
    UMass Chan Affiliations
    New England Center for Stroke Research
    Department of Radiology, Division of Neuroimaging and Intervention
    Document Type
    Journal Article
    Publication Date
    2019-07-01
    Keywords
    Cardiovascular Diseases
    Nervous System Diseases
    Neurology
    Radiology
    Surgery
    
    Metadata
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    Link to Full Text
    https://doi.org/10.3171/2019.4.FOCUS19333
    Abstract
    his issue of Neurosurgical Focus addresses several of the important biological and genetic aspects of aneurysm formation. The reader will be exposed to the latest theories of aneurysm formation that invoke genetic predispositions and the role of inflammation and matrix metalloproteinases in the genesis of a cerebral aneurysm. Observational studies provide additional insight into the role of estrogen and other female sex steroids and tobacco use with respect to the evolution of multiple aneurysms.
    Source

    Neurosurg Focus. 2019 Jul 1;47(1):E1. doi: 10.3171/2019.4.FOCUS19333. Link to article on publisher's site

    DOI
    10.3171/2019.4.FOCUS19333
    Permanent Link to this Item
    http://hdl.handle.net/20.500.14038/48379
    PubMed ID
    31261113
    Related Resources

    Link to Article in PubMed

    ae974a485f413a2113503eed53cd6c53
    10.3171/2019.4.FOCUS19333
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