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LI-RADS treatment response assessment of combination locoregional therapy for HCC

dc.contributor.authorGerena, Marielia
dc.contributor.authorMolvar, Christopher
dc.contributor.authorMasciocchi, Mark
dc.contributor.authorNandwana, Sadhna
dc.contributor.authorSabottke, Carl
dc.contributor.authorSpieler, Bradley
dc.contributor.authorSharma, Rishi
dc.contributor.authorTsai, Leo
dc.contributor.authorKielar, Ania
dc.date2022-08-11T08:10:50.000
dc.date.accessioned2022-08-23T17:21:30Z
dc.date.available2022-08-23T17:21:30Z
dc.date.issued2021-08-01
dc.date.submitted2021-09-03
dc.identifier.citation<p>Gerena M, Molvar C, Masciocchi M, Nandwana S, Sabottke C, Spieler B, Sharma R, Tsai L, Kielar A. LI-RADS treatment response assessment of combination locoregional therapy for HCC. Abdom Radiol (NY). 2021 Aug;46(8):3634-3647. doi: 10.1007/s00261-021-03165-x. Epub 2021 Jun 13. PMID: 34120207. <a href="https://doi.org/10.1007/s00261-021-03165-x">Link to article on publisher's site</a></p>
dc.identifier.issn2366-0058 (Electronic)
dc.identifier.doi10.1007/s00261-021-03165-x
dc.identifier.pmid34120207
dc.identifier.urihttp://hdl.handle.net/20.500.14038/48536
dc.description.abstractHCC incidence continues to increase worldwide and is most frequently discovered at an advanced stage when limited curative options are available. Combination locoregional therapies have emerged to improve patient survival and quality of life or downstage patients to curative options. The increasing options for locoregional therapy combinations require an understanding of the expected post-treatment imaging appearance in order to assess treatment response. This review aims to describe the synergy between TACE combined with thermal ablation and TACE combined with SBRT. We will also illustrate expected imaging findings that determine treatment efficacy based on the mechanism of tissue injury using the LI-RADS Treatment Response Algorithm.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=34120207&dopt=Abstract">Link to Article in PubMed</a></p>
dc.relation.urlhttps://doi.org/10.1007/s00261-021-03165-x
dc.subjectArterial phase hyperenhancement
dc.subjectCombination locoregional therapy
dc.subjectHepatocellular carcinoma
dc.subjectLI-RADS Treatment Response Assessment
dc.subjectSBRT
dc.subjectTACE
dc.subjectThermal ablation
dc.subjectDigestive System Diseases
dc.subjectNeoplasms
dc.subjectRadiology
dc.titleLI-RADS treatment response assessment of combination locoregional therapy for HCC
dc.typeJournal Article
dc.source.journaltitleAbdominal radiology (New York)
dc.source.volume46
dc.source.issue8
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/radiology_pubs/636
dc.identifier.contextkey24651271
html.description.abstract<p>HCC incidence continues to increase worldwide and is most frequently discovered at an advanced stage when limited curative options are available. Combination locoregional therapies have emerged to improve patient survival and quality of life or downstage patients to curative options. The increasing options for locoregional therapy combinations require an understanding of the expected post-treatment imaging appearance in order to assess treatment response. This review aims to describe the synergy between TACE combined with thermal ablation and TACE combined with SBRT. We will also illustrate expected imaging findings that determine treatment efficacy based on the mechanism of tissue injury using the LI-RADS Treatment Response Algorithm.</p>
dc.identifier.submissionpathradiology_pubs/636
dc.contributor.departmentDepartment of Radiology
dc.source.pages3634-3647


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