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dc.contributor.authorMarya, Neil B
dc.contributor.authorKarellas, Andrew
dc.contributor.authorFoley, Anne
dc.contributor.authorRoychowdhury, Abhijit
dc.contributor.authorCave, David R.
dc.date2022-08-11T08:10:50.000
dc.date.accessioned2022-08-23T17:21:44Z
dc.date.available2022-08-23T17:21:44Z
dc.date.issued2014-04-01
dc.date.submitted2014-12-23
dc.identifier.citationGastrointest Endosc. 2014 Apr;79(4):669-74. doi: 10.1016/j.gie.2013.11.022. Epub 2014 Jan 11. <a href="http://dx.doi.org/10.1016/j.gie.2013.11.022">Link to article on publisher's site</a>
dc.identifier.issn0016-5107 (Linking)
dc.identifier.doi10.1016/j.gie.2013.11.022
dc.identifier.pmid24424401
dc.identifier.urihttp://hdl.handle.net/20.500.14038/48590
dc.description.abstractBACKGROUND: Wireless video capsule endoscopy allows the noninvasive visualization of the small intestine. Currently, capsules do not provide localization information while traversing the GI tract. OBJECTIVE: To report on the radiological validation of 3-dimensional localization software incorporated in a newly developed capsule. By using radiofrequency transmission, the software measures the strength of the capsule's signal to locate the position of the capsule. SETTING: This study was performed at the University of Massachusetts Medical Center, Worcester, Mass. PATIENTS: Thirty healthy volunteers consented to the experimental procedure. DESIGN: After ingestion of the capsule, subjects had 5 sets of anteroposterior and lateral radiographs taken every 30 minutes while the software calculated the position of the capsule. By using the radiographs, we calculated the location of the capsule in the abdominal cavity and compared the results with those generated by the software. RESULTS: Average error (and standard deviation) among the 3-dimensional coordinates was X, 2.00 cm (1.64); Y, 2.64 cm (2.39); and Z, 2.51 cm (1.83). The average total spatial error among all measurements was 13.26 cm(3) (22.72). There was a correlation between increased subject body mass index and the 3-dimensional software measurement error. LIMITATIONS: This study was performed in healthy volunteers and needs further validation in patients with small intestinal disorders. CONCLUSIONS: The new 3-dimensional software provides localization of the capsule consistent with radiological observations. However, further validation of the software's clinical utility is required with a prospective clinical trial. Mosby, Inc. All rights reserved.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=24424401&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1016/j.gie.2013.11.022
dc.subjectAbdominal Cavity
dc.subject*Capsule Endoscopy
dc.subjectFemale
dc.subjectHumans
dc.subject*Imaging, Three-Dimensional
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectProspective Studies
dc.subject*Radiographic Image Enhancement
dc.subjectSoftware
dc.subjectDiagnosis
dc.subjectGastroenterology
dc.subjectInvestigative Techniques
dc.subjectRadiology
dc.titleComputerized 3-dimensional localization of a video capsule in the abdominal cavity: validation by digital radiography
dc.typeJournal Article
dc.source.journaltitleGastrointestinal endoscopy
dc.source.volume79
dc.source.issue4
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/radiology_pubs/78
dc.identifier.contextkey6488697
html.description.abstract<p>BACKGROUND: Wireless video capsule endoscopy allows the noninvasive visualization of the small intestine. Currently, capsules do not provide localization information while traversing the GI tract.</p> <p>OBJECTIVE: To report on the radiological validation of 3-dimensional localization software incorporated in a newly developed capsule. By using radiofrequency transmission, the software measures the strength of the capsule's signal to locate the position of the capsule.</p> <p>SETTING: This study was performed at the University of Massachusetts Medical Center, Worcester, Mass.</p> <p>PATIENTS: Thirty healthy volunteers consented to the experimental procedure.</p> <p>DESIGN: After ingestion of the capsule, subjects had 5 sets of anteroposterior and lateral radiographs taken every 30 minutes while the software calculated the position of the capsule. By using the radiographs, we calculated the location of the capsule in the abdominal cavity and compared the results with those generated by the software.</p> <p>RESULTS: Average error (and standard deviation) among the 3-dimensional coordinates was X, 2.00 cm (1.64); Y, 2.64 cm (2.39); and Z, 2.51 cm (1.83). The average total spatial error among all measurements was 13.26 cm(3) (22.72). There was a correlation between increased subject body mass index and the 3-dimensional software measurement error.</p> <p>LIMITATIONS: This study was performed in healthy volunteers and needs further validation in patients with small intestinal disorders.</p> <p>CONCLUSIONS: The new 3-dimensional software provides localization of the capsule consistent with radiological observations. However, further validation of the software's clinical utility is required with a prospective clinical trial. Mosby, Inc. All rights reserved.</p>
dc.identifier.submissionpathradiology_pubs/78
dc.contributor.departmentDepartment of Medicine, Division of Gastroenterology
dc.contributor.departmentDepartment of Radiology
dc.source.pages669-74


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