Cross-vender, cross-tracer, and cross-protocol deep transfer learning for attenuation map generation of cardiac SPECT
Authors
Chen, XiongchaoPretorius, P. Hendrik
Zhou, Bo
Liu, Hui
Johnson, Karen L.
Liu, Yi-Hwa
King, Michael A.
Liu, Chi
UMass Chan Affiliations
Department of RadiologyDocument Type
Journal ArticlePublication Date
2022-04-26Keywords
Attenuation map generationSPECT/CT
myocardial perfusion imaging
transfer learning
Biological and Chemical Physics
Cardiology
Medical Biophysics
Radiology
Metadata
Show full item recordAbstract
It has been proved feasible to generate attenuation maps (mu-maps) from cardiac SPECT using deep learning. However, this assumed that the training and testing datasets were acquired using the same scanner, tracer, and protocol. We investigated a robust generation of CT-derived mu-maps from cardiac SPECT acquired by different scanners, tracers, and protocols from the training data. We first pre-trained a network using 120 studies injected with (99m)Tc-tetrofosmin acquired from a GE 850 SPECT/CT with 360-degree gantry rotation, which was then fine-tuned and tested using 80 studies injected with (99m)Tc-sestamibi acquired from a Philips BrightView SPECT/CT with 180-degree gantry rotation. The error between ground-truth and predicted mu-maps by transfer learning was 5.13 +/- 7.02%, as compared to 8.24 +/- 5.01% by direct transition without fine-tuning and 6.45 +/- 5.75% by limited-sample training. The error between ground-truth and reconstructed images with predicted mu-maps by transfer learning was 1.11 +/- 1.57%, as compared to 1.72 +/- 1.63% by direct transition and 1.68 +/- 1.21% by limited-sample training. It is feasible to apply a network pre-trained by a large amount of data from one scanner to data acquired by another scanner using different tracers and protocols, with proper transfer learning.Source
Chen X, Hendrik Pretorius P, Zhou B, Liu H, Johnson K, Liu YH, King MA, Liu C. Cross-vender, cross-tracer, and cross-protocol deep transfer learning for attenuation map generation of cardiac SPECT. J Nucl Cardiol. 2022 Apr 26. doi: 10.1007/s12350-022-02978-7. Epub ahead of print. PMID: 35474443. Link to article on publisher's site
DOI
10.1007/s12350-022-02978-7Permanent Link to this Item
http://hdl.handle.net/20.500.14038/48646PubMed ID
35474443Related Resources
ae974a485f413a2113503eed53cd6c53
10.1007/s12350-022-02978-7